Yi Zang, Ruo-nan Sun, Ran-qi Feng, Hong-hui Zhu, Xu-wen Li
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Recent Advances of Terpenoids with Intriguing Chemical Skeletons and Biological Activities
Terpenoids are a large and diverse family of secondary metabolites that have gained more attention from chemists and pharmacologists for their intriguing skeletons and broad biological activities, including anti-inflammatory, antitumoral, antimicrobial, and anti-viral effects. Based on the previous reviews, this review comprehensively summarized recent advances on bioactive terpenoids, focusing on their intriguing structural features and promising biological activities, covering literature from 2020 to 2023. In this review, 532 terpenoids with remarkable chemical architectures and biological properties are classified into sesquiterpenoids (142), diterpenoids (129), sesterterpenoids (24), triterpenoids (52), and meroterpenoids (185), that were isolated from terrestrial and marine resources. This review would provide a reference for researchers to rapidly discover the interesting terpenoids for further study as promising drug leads.
期刊介绍:
The Chinese Journal of Chemistry is an international forum for peer-reviewed original research results in all fields of chemistry. Founded in 1983 under the name Acta Chimica Sinica English Edition and renamed in 1990 as Chinese Journal of Chemistry, the journal publishes a stimulating mixture of Accounts, Full Papers, Notes and Communications in English.