Kiran Manjunatha, Anna Ranno, Jianye Shi, Nicole Schaaps, Pakhwan Nilcham, Anne Cornelissen, Felix Vogt, Marek Behr, Stefanie Reese
{"title":"考虑血流动力学效应的支架内再狭窄的连续化学-力学-生物学模型","authors":"Kiran Manjunatha, Anna Ranno, Jianye Shi, Nicole Schaaps, Pakhwan Nilcham, Anne Cornelissen, Felix Vogt, Marek Behr, Stefanie Reese","doi":"10.1002/gamm.202370008","DOIUrl":null,"url":null,"abstract":"<p>The occurrence of in-stent restenosis following percutaneous coronary intervention highlights the need for the creation of computational tools that can extract pathophysiological insights and optimize interventional procedures on a patient-specific basis. In light of this, a modeling framework encompassing the chemo-mechano-biological interactions in the arterial wall and the effects of hemodynamic perturbations is introduced in this work.</p>","PeriodicalId":53634,"journal":{"name":"GAMM Mitteilungen","volume":"48 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gamm.202370008","citationCount":"0","resultStr":"{\"title\":\"A continuum chemo-mechano-biological model for in-stent restenosis with consideration of hemodynamic effects\",\"authors\":\"Kiran Manjunatha, Anna Ranno, Jianye Shi, Nicole Schaaps, Pakhwan Nilcham, Anne Cornelissen, Felix Vogt, Marek Behr, Stefanie Reese\",\"doi\":\"10.1002/gamm.202370008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The occurrence of in-stent restenosis following percutaneous coronary intervention highlights the need for the creation of computational tools that can extract pathophysiological insights and optimize interventional procedures on a patient-specific basis. In light of this, a modeling framework encompassing the chemo-mechano-biological interactions in the arterial wall and the effects of hemodynamic perturbations is introduced in this work.</p>\",\"PeriodicalId\":53634,\"journal\":{\"name\":\"GAMM Mitteilungen\",\"volume\":\"48 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gamm.202370008\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"GAMM Mitteilungen\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/gamm.202370008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Mathematics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"GAMM Mitteilungen","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/gamm.202370008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Mathematics","Score":null,"Total":0}
A continuum chemo-mechano-biological model for in-stent restenosis with consideration of hemodynamic effects
The occurrence of in-stent restenosis following percutaneous coronary intervention highlights the need for the creation of computational tools that can extract pathophysiological insights and optimize interventional procedures on a patient-specific basis. In light of this, a modeling framework encompassing the chemo-mechano-biological interactions in the arterial wall and the effects of hemodynamic perturbations is introduced in this work.