Kiran Manjunatha, Anna Ranno, Jianye Shi, Nicole Schaaps, Pakhwan Nilcham, Anne Cornelissen, Felix Vogt, Marek Behr, Stefanie Reese
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A continuum chemo-mechano-biological model for in-stent restenosis with consideration of hemodynamic effects
The occurrence of in-stent restenosis following percutaneous coronary intervention highlights the need for the creation of computational tools that can extract pathophysiological insights and optimize interventional procedures on a patient-specific basis. In light of this, a modeling framework encompassing the chemo-mechano-biological interactions in the arterial wall and the effects of hemodynamic perturbations is introduced in this work.
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