封面专题:将金属有机配体设计原理应用于多肽基Pd2L4X4笼的立体选择性合成(ChemistryEurope 1/2025)

Dr. Dominic F. Brightwell, Dr. Kushal Samanta, Dr. Jimmy Muldoon, Dr. Patricia C. Fleming, Dr. Yannick Ortin, Dr. Lina Mardiana, Dr. Paul G. Waddell, Dr. Michael J. Hall, Dr. Ewan R. Clark, Dr. Felipe Fantuzzi, Dr. Aniello Palma
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引用次数: 0

摘要

封面特征庆祝立体选择性合成肽基钯笼。手性、低对称性肽基配体用于生成Pd笼,理论上可以产生多达四种结构异构体。值得注意的是,溶液中只形成一个同分异构体笼,即热力学稳定的笼。这幅图像代表了从所有可能的异构体中脱颖而出的单一异构体,在背景中以不同的颜色显示。更多信息可以在A. Palma及其同事的研究文章中找到(DOI: 10.1002/ eur.202400050)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Cover Feature: Applying Metallo-Organic Ligand Design Principles to the Stereoselective Synthesis of a Peptide-Based Pd2L4X4 Cage (ChemistryEurope 1/2025)

Cover Feature: Applying Metallo-Organic Ligand Design Principles to the Stereoselective Synthesis of a Peptide-Based Pd2L4X4 Cage (ChemistryEurope 1/2025)

The Cover Feature celebrates the stereoselective synthesis of a peptide-based palladium cage. The chiral, low-symmetry peptide-based ligand used to generate this Pd cage could theoretically yield up to four structural isomers. Remarkably, only a single isomeric cage is formed in solution, the thermodynamically stable one. The image represents the single isomer emerging into the spotlight from all the possible isomers, shown in different colours in the background. More information can be found in the Research Article by A. Palma and co-workers (DOI: 10.1002/ceur.202400050).

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