孤立性注意缺陷障碍和1型神经纤维瘤病相关注意缺陷障碍在治疗上的差异

Q3 Medicine

Revista Colombiana de Psiquiatria Pub Date : 2024-10-01 DOI:10.1016/j.rcp.2022.05.003

Esteban Vaucheret Paz, Rosario Ortolá, Matias Cestari, Francisco Cordoba, Mariana Leist, Luciana Petracca, Claudia Chirilla, Ignacio Appendino

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引用次数: 0

摘要

NF1患者ADHD发生率达60%。除了已发表的关于NF1受试者认知方面的文献外，一些研究表明NF1+ADHD患者的注意力特征与孤立性ADHD患者不同。方法采用回顾性、分析性病例对照研究，比较NF1+ADHD、NF1和孤立性ADHD患儿的智力和注意力特征，并分析其异同。结果回顾了2017 - 2021年所有诊断为NF1 (n = 46), IQ >；70和ADHD （n = 180）的受试者的神经心理学评估。方差分析发现，NF1+ADHD患者表现出更大的视觉空间障碍(M = 84.66；f (2210) = 7.84；术中;0.001;η2 = 0.07)，总智力水平较低(M = 84.20；f (2,223) = 4.35；p = 0.01；η2 = 0.04)。在注意力测试中，他们表现出更多的遗漏错误(M = 72.66；f (2,223) = 18.13；术中;措施;η2 = 0.14)和佣金(M = 57.87；f (2,223) = 4.68；p = 0.01；η2 = 0.04)，反应速度较慢(M = 66.58；f (2223) = 19.24；术中;0.001;η2 = 0.15)，与NF1和孤立性ADHD患者相比。结论NF1患者的注意缺陷与较低的智力功能表现和较大的视觉空间损害有关。NF1+ADHD患者的注意模式与孤立性ADHD患者不同；这种差异不仅是定量的，而且是定性的，支持了注意缺陷有其自身的NF1特征，独立于ADHD的假设。

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Diferencias atencionales entre el trastorno por déficit de atención aislado y asociado a neurofibromatosis tipo 1

Introduction

The incidence of ADHD in patients with NF1 reaches 60%. Beyond the published literature on cognitive aspects in subjects with NF1, some studies suggest that the attentional profile of patients with NF1+ADHD is different from those with isolated ADHD.

Methods

A retrospective, analytical case-control study with the objective of comparing the intellectual and attentional profile in children with NF1+ADHD, NF1 and isolated ADHD in order to characterise them, noting similarities and differences.

Results

Neuropsychological evaluations from 2017 to 2021 were reviewed for all subjects with a diagnosis of NF1 (n = 46) with IQ >70 and ADHD (n = 180). In the ANOVA test, it was observed that patients with NF1+ADHD presented with greater visuospatial impairment (M = 84.66; F_(2,210) = 7.84; P< 0.001; η² = 0.07) and a lower total intellectual level (M = 84.20; F_(2,223) = 4.35; P = 0.01; η² = 0.04). In the attentional tests they showed more errors of omission (M = 72.66; F_(2,223) = 18.13; P< .001; η² = 0.14) and of commission (M = 57.87; F_(2,223) = 4.68; P = 0.01; η² = 0.04) and lower reaction speed (M = 66.58; F_(2,223) = 19.24; P< 0.001; η² = 0.15) compared to patients with NF1 and isolated ADHD.

Conclusions

Attention deficit in patients with NF1 is associated with lower performance in intellectual functioning and greater visuospatial impairment. The attentional pattern of patients with NF1+ADHD was different from those with isolated ADHD; the difference being not only quantitative but also qualitative, supporting the hypothesis that attention impairment has its own features of NF1 and independent of ADHD.

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来源期刊

Revista Colombiana de Psiquiatria Medicine-Psychiatry and Mental Health

CiteScore

2.50

自引率

0.00%

发文量

期刊介绍： Revista Colombiana de Psiquiatría (RCP) is a quarterly official publication of Colombian Psychiatry Association (March, June, September and December) and its purpose is to spread different the knowledge models that currently constitute the theoretical and practical body of our specialty. Psychiatrists, psychiatric residents, non psychiatric physicians, psychologists, philosophers or other health professionals or persons interested in this area can take part in the magazine. This journal publishes original works, revision or updating articles, case reports of all psychiatry and mental health areas, epistemology, mind philosophy, bioethics and also articles about methodology of investigation and critical reading.