贝尔瘫痪和COVID -19：历史比较队列研究

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola Pub Date : 2025-01-01 DOI:10.1016/j.otorri.2024.07.006

Natalia Arango , María Jesús Rojas-Lechuga , Jiwei Chen , Francisco Larrosa , Berta Alegre , Isabel Vilaseca

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引用次数: 0

摘要

在SARS-CoV-2大流行期间，已在接种该病毒疫苗或已克服该疾病的患者中描述了免疫介导的神经事件。这些事件包括特发性周围性面瘫或贝尔麻痹。目的了解新冠肺炎大流行期间加泰罗尼亚某三级医院耳鼻喉急诊科贝尔氏麻痹的发病率。方法对2018年1月至2021年12月诊断为贝尔麻痹的患者进行回顾性历史队列比较研究。粗发病率计算为事件总数除以每100,000人年的风险时间。观察（2020年、2021年）和历史（2018年、2019年）的发病率采用标准化发病率和相应的95%置信区间进行比较。结果2018 - 2021年耳鼻喉科急诊就诊人次（22.658人次）中，贝尔麻痹247例。2018年和2019年，大流行前组贝尔氏麻痹的发病率分别为每10万人年12.2例和10.9例。2020年贝尔麻痹的标准化发病率为0.70 (95% CI: 0.49 -1,01)， 2021年为1.25 （95% CI: 0.93 -1,67）。两组间无明显差异。结论在我们的队列中，未发现疫苗接种或COVID-19感染与贝尔麻痹的发生有关。

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Parálisis de Bell y covid-19: estudio de cohortes de comparación histórica

Introduction

During the SARS-CoV-2 pandemic, immune-mediated neurological events have been described in patients vaccinated against the virus or who have overcome the disease. Among these events is idiopathic peripheral facial palsy or Bell's palsy.

Objectives

To study the incidence of Bell's palsy in the ENT emergency department of a tertiary hospital in Catalonia during the SARS-CoV-2 pandemic.

Methods

Retrospective historical cohort comparison study of patients diagnosed with Bell's palsy between January 2018 and December 2021. Crude incidence rates were calculated as the total number of events divided by person time at risk per 100.000 person-years. Observed (2020, 2021) and historical (2018, 2019) rates were compared using standardized incidence rates with corresponding 95% confidence intervals.

Results

Of the total number of ENT emergency department visits from 2018 to 2021 (22.658), there were 247 cases of Bell's palsy. The incidence rate of Bell's palsy in the pre-pandemic group was 12,2 and 10,9 per 100.000 person-years for 2018 and 2019, respectively. The 2020 standardized incidence rate of Bell's palsy was 0,70 (95% CI: 0,49-1,01) and 1,25 (95% CI: 0,93-1,67) for 2021. No significant differences were evident between the 2 groups.

Conclusion

In our cohort, no association was found between vaccination or COVID-19 infection and the development of Bell's palsy.

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来源期刊

Acta otorrinolaringologica espanola OTORHINOLARYNGOLOGY-

CiteScore

1.40

自引率

20.00%

发文量

审稿时长

44 days

期刊介绍： Es la revista más importante en español dedicada a la especialidad. Ofrece progresos científicos y técnicos tanto a nivel de originales como de casos clínicos. Además, es la Publicación Oficial de la Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial y está presente en los más prestigiosos índices de referencia.