Alkaloids of the roots of Lindera glauca (Lauraceae) and their chemophenetics significance

Phytochemical investigation of the roots of Lindera glauca led to the isolation of 14 compounds, including four lignanamides (1–4), six hydroxycinnamic acid amides (HCCAs) (5–10), three isoquinoline alkaloids (11–13), and one purine (14). These structures were elucidated on the basis of 1D and 2D NMR spectra (COSY, HSQC, HMBC, and ROESY) and HRESIMS data. Importantly, compound 1 was identified as a new lignanamide derivative, and compounds 2–4 are reported from the Lindera genus for the first time. Meanwhile, compounds 11–14 were reported from the Lauraceae family for the first time. Furthermore, chemophenetics significance of these isolates was also discussed.