含酯杯[n]苯恶嗪：侧链增强识别和氧化还原反应可逆主客体系统

IF 3.6 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2025-01-22 DOI:10.1021/acs.joc.4c0286410.1021/acs.joc.4c02864

Lu Wang, Yujun Zhang, Junhao Chen, Sanhanut Jongaksorn, Zhihao Lu, Xin Zhang, Shuo Li, Chenghao Zhu, Da Ma* and Lijun Mao*,

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引用次数: 0

摘要

我们报道了一种基于含酯杯[n]苯恶嗪的增强识别和氧化还原反应的可逆主-客体系统。面向空腔的羰基作为额外的结合位点，增强了结合亲和力，通过NMR和FTIR实验以及单晶结构分析证实了这一点。由于杯[n]苯恶嗪的可氧化性，建立了氧化还原控制的可逆反应。本研究不仅为提高杯状大环芳烃的结合亲和力提供了一种策略，而且标志着基于大环芳烃的可逆响应体系的发展取得了重大进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Ester-Bearing Calix[n]phenoxazines: Side Chain Enhanced Recognition and Redox-Responsive Reversible Host–Guest System

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Ester-Bearing Calix[n]phenoxazines: Side Chain Enhanced Recognition and Redox-Responsive Reversible Host–Guest System

We report an enhanced recognition and redox-responsive reversible host–guest system based on ester-bearing calix[n]phenoxazines. The carbonyl groups, oriented toward the cavity, act as the extra binding sites to enhance the binding affinity, which is confirmed by NMR and FTIR experiments and single-crystal structure analysis. Due to the oxidizable nature of calix[n]phenoxazine, a redox-controlled reversible response is established. This research not only provides a strategy to enhance the binding affinity in calix-like macrocyclic arenes but also marks a major advance in the development of a macrocyclic arene-based reversibly responsive system.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.