Ni Cui, Qiuxia Li, Jing Cheng, Tianhua Xing, Peiyao Shi, Yingmei Wang, Min Luo, Yaoshan Dun, Suixin Liu
{"title":"老年人代谢综合征与心脏自主神经功能和心肺健康之间的关系：倾向评分重叠加权的回顾性观察研究。","authors":"Ni Cui, Qiuxia Li, Jing Cheng, Tianhua Xing, Peiyao Shi, Yingmei Wang, Min Luo, Yaoshan Dun, Suixin Liu","doi":"10.2147/CIA.S489409","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Delayed heart rate recovery (HRR) after exercise, an indicator of cardiac autonomic nervous function (CANF), has been found to be associated with metabolic syndrome (MetS) in general populations. However, this relationship has not been extensively studied in older adults. The present study aimed to investigate the association between MetS and HRRs at 1, 2, 3 and 6 minutes after exercise and cardiorespiratory fitness (CRF) in Chinese dwelling older adults.</p><p><strong>Methods: </strong>This retrospective, observational study consecutively enrolled participants aged 60 years or older who underwent physical examinations in Shenzhen District Yantian People's Hospital from September 2019 to July 2021. The participants were categorized into MetS and non-MetS groups according to the International Diabetes Federation criteria. Logistic regression analysis was applied to assess the association between MetS and CANF and CRF. Propensity score overlap weighting was used to adjust the covariates.</p><p><strong>Results: </strong>A total of 987 eligible participants were included (mean age±SD, 66±4 years; male, 47.1%), of whom, 506 were diagnosed with MetS. MetS group showed significantly lower peak heart rate, HRR1-3, HRR6, peak metabolic equivalents, and peak oxygen consumption compared to the non-MetS group. Furthermore, peak systolic and diastolic blood pressures in the MetS group were significantly higher. Logistic regression analysis showed that MetS was significantly associated with HRR2, HRR3 (odds ratio [95% CI], 0.997 [0.995,0.999], both; <i>P</i>=0.009 and 0.005, respectively) and HRR6 (0.996 [0.994,0.998], <i>P</i><0.001). The association between MetS and CRF was significant (0.98 [0.97,0.98], <i>P</i><0.001).</p><p><strong>Conclusion: </strong>Elderly Chinese with MetS tend to exhibit reduced CANF and lower CRF. It is recommended that they boost physical activity and closely monitor heart rate and blood pressure during exercise to mitigate exercise-related risks.</p>","PeriodicalId":48841,"journal":{"name":"Clinical Interventions in Aging","volume":"20 ","pages":"93-105"},"PeriodicalIF":3.5000,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787786/pdf/","citationCount":"0","resultStr":"{\"title\":\"Association Between Metabolic Syndrome and Cardiac Autonomic Nervous Function and Cardiorespiratory Fitness in Older Adults: A Retrospective Observational Study with Propensity Score Overlap Weighting.\",\"authors\":\"Ni Cui, Qiuxia Li, Jing Cheng, Tianhua Xing, Peiyao Shi, Yingmei Wang, Min Luo, Yaoshan Dun, Suixin Liu\",\"doi\":\"10.2147/CIA.S489409\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Delayed heart rate recovery (HRR) after exercise, an indicator of cardiac autonomic nervous function (CANF), has been found to be associated with metabolic syndrome (MetS) in general populations. However, this relationship has not been extensively studied in older adults. The present study aimed to investigate the association between MetS and HRRs at 1, 2, 3 and 6 minutes after exercise and cardiorespiratory fitness (CRF) in Chinese dwelling older adults.</p><p><strong>Methods: </strong>This retrospective, observational study consecutively enrolled participants aged 60 years or older who underwent physical examinations in Shenzhen District Yantian People's Hospital from September 2019 to July 2021. The participants were categorized into MetS and non-MetS groups according to the International Diabetes Federation criteria. Logistic regression analysis was applied to assess the association between MetS and CANF and CRF. Propensity score overlap weighting was used to adjust the covariates.</p><p><strong>Results: </strong>A total of 987 eligible participants were included (mean age±SD, 66±4 years; male, 47.1%), of whom, 506 were diagnosed with MetS. MetS group showed significantly lower peak heart rate, HRR1-3, HRR6, peak metabolic equivalents, and peak oxygen consumption compared to the non-MetS group. Furthermore, peak systolic and diastolic blood pressures in the MetS group were significantly higher. Logistic regression analysis showed that MetS was significantly associated with HRR2, HRR3 (odds ratio [95% CI], 0.997 [0.995,0.999], both; <i>P</i>=0.009 and 0.005, respectively) and HRR6 (0.996 [0.994,0.998], <i>P</i><0.001). The association between MetS and CRF was significant (0.98 [0.97,0.98], <i>P</i><0.001).</p><p><strong>Conclusion: </strong>Elderly Chinese with MetS tend to exhibit reduced CANF and lower CRF. It is recommended that they boost physical activity and closely monitor heart rate and blood pressure during exercise to mitigate exercise-related risks.</p>\",\"PeriodicalId\":48841,\"journal\":{\"name\":\"Clinical Interventions in Aging\",\"volume\":\"20 \",\"pages\":\"93-105\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-01-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787786/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Interventions in Aging\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/CIA.S489409\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Interventions in Aging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/CIA.S489409","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
Association Between Metabolic Syndrome and Cardiac Autonomic Nervous Function and Cardiorespiratory Fitness in Older Adults: A Retrospective Observational Study with Propensity Score Overlap Weighting.
Background: Delayed heart rate recovery (HRR) after exercise, an indicator of cardiac autonomic nervous function (CANF), has been found to be associated with metabolic syndrome (MetS) in general populations. However, this relationship has not been extensively studied in older adults. The present study aimed to investigate the association between MetS and HRRs at 1, 2, 3 and 6 minutes after exercise and cardiorespiratory fitness (CRF) in Chinese dwelling older adults.
Methods: This retrospective, observational study consecutively enrolled participants aged 60 years or older who underwent physical examinations in Shenzhen District Yantian People's Hospital from September 2019 to July 2021. The participants were categorized into MetS and non-MetS groups according to the International Diabetes Federation criteria. Logistic regression analysis was applied to assess the association between MetS and CANF and CRF. Propensity score overlap weighting was used to adjust the covariates.
Results: A total of 987 eligible participants were included (mean age±SD, 66±4 years; male, 47.1%), of whom, 506 were diagnosed with MetS. MetS group showed significantly lower peak heart rate, HRR1-3, HRR6, peak metabolic equivalents, and peak oxygen consumption compared to the non-MetS group. Furthermore, peak systolic and diastolic blood pressures in the MetS group were significantly higher. Logistic regression analysis showed that MetS was significantly associated with HRR2, HRR3 (odds ratio [95% CI], 0.997 [0.995,0.999], both; P=0.009 and 0.005, respectively) and HRR6 (0.996 [0.994,0.998], P<0.001). The association between MetS and CRF was significant (0.98 [0.97,0.98], P<0.001).
Conclusion: Elderly Chinese with MetS tend to exhibit reduced CANF and lower CRF. It is recommended that they boost physical activity and closely monitor heart rate and blood pressure during exercise to mitigate exercise-related risks.
期刊介绍：
Clinical Interventions in Aging, is an online, peer reviewed, open access journal focusing on concise rapid reporting of original research and reviews in aging. Special attention will be given to papers reporting on actual or potential clinical applications leading to improved prevention or treatment of disease or a greater understanding of pathological processes that result from maladaptive changes in the body associated with aging. This journal is directed at a wide array of scientists, engineers, pharmacists, pharmacologists and clinical specialists wishing to maintain an up to date knowledge of this exciting and emerging field.
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