熊果酸的研究进展及其潜在的生物学应用。

Q1 Environmental Science

Toxicology Reports Pub Date : 2025-01-10 DOI:10.1016/j.toxrep.2025.101900

R. Arulnangai , H. Asia Thabassoom , H. Vajiha Banu , K. Thirugnanasambandham , R. Ganesamoorthy

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引用次数: 0

摘要

熊果酸（UA）是一种天然存在的五环三萜，由于其各种药理特性和医学用途而引起了人们的极大兴趣。这篇综述的目的是全面研究UA的治疗益处，包括其抗炎、抗氧化、抗癌、抗菌和代谢调节特性。我们将讨论它的起源、药理学特征以及在治疗几种疾病方面的优势，包括癌症、神经系统疾病、代谢紊乱和心血管疾病。我们进一步强调其提高运动能力的潜力及其作为运动模拟物的日益增长的功能。UA的治疗潜力在这篇综述中得到了充分的解释，其中强调了该化合物作为几种疾病的天然药物的潜力。

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Recent developments on ursolic acid and its potential biological applications

A naturally occurring pentacyclic triterpenoid, ursolic acid (UA) has attracted a lot of interest due to its various pharmacological characteristics and its medical uses. The goal of this thorough review is to present a thorough examination of the therapeutic benefits of UA, including its anti-inflammatory, antioxidant, anticancer, antibacterial, and metabolic-regulating properties. We go over its origins, pharmacological characteristics, and advantages in the treatment of several illnesses, including cancer, neurological disorders, metabolic disorders, and cardiovascular diseases. We further emphasize its potential to improve exercise capacity and its growing function as an exercise mimic. UA's therapeutic potential is thoroughly explained in this review, which highlights the compound's potential as a natural remedy for several illnesses.

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