球囊二尖瓣成形术前后肺脉冲传递时间对肺动脉血流动力学的评价。

IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Journal of Cardiovascular Echography Pub Date : 2024-10-01 Epub Date: 2024-12-19 DOI:10.4103/jcecho.jcecho_44_24
Mohamed Saeed Abdelmordy Abdallah, Amany Ragab Mahmoud Serag, Mohamed Yahia Abd Elkhalek, Fatma Elzahraa Abdelmonem Zein
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引用次数: 0

摘要

背景:经胸超声心动图仍然是鉴别肺动脉高压(PAH)的重要诊断工具。我们热切期待新的无创技术的发展,这将大大提高我们对肺循环和右心室的认识。目的:本研究的目的是利用肺脉冲传递时间(pPTT)评估球囊二尖瓣成形术(BMV)后的肺动脉血流动力学。患者和方法:33例中重度二尖瓣狭窄伴不同程度肺动脉高压的患者到美国国家心脏研究所行经皮二尖瓣球囊成形术。评估参与者的超声心动图变量,包括pPTT,并在BMV后立即、1周、1个月和6个月进行随访。结果:研究表明,BMV后右心室分数面积变化和三尖瓣环平面收缩偏移(TAPSE)有显著的进行性改善;另一方面,肺动脉收缩压在术后和随访期间明显降低。在分析中,我们发现手术后pPTT值有显著变化(P < 0.001)。该值在手术后立即显著下降,并在随后的随访期间继续下降。每项术后测量均显示较基线显著降低(P < 0.001)。结论:MS患者毛细血管后肺动脉高压患者pPTT升高,病理纠正后pPTT降低;pPTT是评价BMV术后PAH改善的有效指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pulmonary Arterial Hemodynamic Assessment by Pulmonary Pulse Transit Time before and after Balloon Mitral Valvuloplasty.

Background: Transthoracic echocardiography remains a crucial diagnostic tool for the identification of pulmonary arterial hypertension (PAH). We eagerly await the novel noninvasive techniques development that significantly advances our knowledge of the pulmonary circulation and right ventricle.

Objective: The objective of this study was to assess pulmonary arterial hemodynamics using pulmonary pulse transit time (pPTT) following balloon mitral valvuloplasty (BMV).

Patients and methods: Thirty-three patients with moderate-to-severe mitral stenosis (MS) with varying pulmonary hypertension degree who were presented to the National Heart Institute to do percutaneous mitral balloon valvuloplasty. Participants were evaluated for their echocardiographic variables including the pPTT, and they were followed up immediately, 1 week, 1 month, and 6 months after BMV.

Results: The study demonstrated a significant and progressive improvement in the right ventricular fractional area change and the tricuspid annular plane systolic excursion (TAPSE) following BMV; on the other hand, the pulmonary artery systolic pressure demonstrated a significant decrease postprocedure and during the follow-up period. On analysis, we found a significant change observed in pPTT values postprocedure (P < 0.001). This value showed a significant reduction immediately following the procedure and the decline continued over the subsequent follow-up periods. Each of these postprocedure measurements showed a significant decrease from the baseline (P < 0.001).

Conclusion: The pPTT was high in postcapillary pulmonary hypertension (in MS patients) and reduced after correction of causative pathology; the pPTT is a valid measure to assess the improvement in PAH after BMV.

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来源期刊
Journal of Cardiovascular Echography
Journal of Cardiovascular Echography CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
1.40
自引率
12.50%
发文量
27
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