Diksha Singh, Ankur Srivastava, Vivek K Chaturvedi, Jay Singh
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This novel hybrid material combines organic CS and inorganic WS<sub>2</sub> components applied for nonenzymatic histamine detection via differential pulse voltammetry. This study also included crystallite size determination and surface morphology assessment through characterization of the synthesized WS<sub>2</sub> nanosheets. On the surface of the SPE, WS<sub>2</sub> and CS were drop-casted. It is recommended that histamine be electrochemically measured on modified WS<sub>2</sub>/CS/SPE electrodes. Histamine measurements were conducted within a linear coverage of 1-100 μM, with a limit of detection of 0.0844 μM and sensitivity of 1.44 × 10<sup>-4</sup> mA/μM cm<sup>2</sup>. The developed sensor exhibited notable levels of sensitivity, selectivity, stability, and repeatability, along with an extended linear range. The sensing technique was consequently employed to detect the histamine levels in packed food items like fermented food samples (cheese, tomato sauce, tomato ketchup, and soy sauce) at room temperature (25 °C). The findings recommend the utilization of electrochemical sensing on modified WS<sub>2</sub>/CS/SPE electrodes for accurate histamine detection.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 3","pages":"3153-3164"},"PeriodicalIF":4.3000,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780422/pdf/","citationCount":"0","resultStr":"{\"title\":\"Nanostructured WS<sub>2</sub>@Chitosan-Modified Screen-Printed Carbon Electrodes for Efficient Amperometric Detection of Histamine.\",\"authors\":\"Diksha Singh, Ankur Srivastava, Vivek K Chaturvedi, Jay Singh\",\"doi\":\"10.1021/acsomega.4c10419\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Histamine, a pivotal chemical within certain cells of the human body, is responsible for eliciting various allergic symptoms, such as sneezing and a runny nose. 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It is recommended that histamine be electrochemically measured on modified WS<sub>2</sub>/CS/SPE electrodes. Histamine measurements were conducted within a linear coverage of 1-100 μM, with a limit of detection of 0.0844 μM and sensitivity of 1.44 × 10<sup>-4</sup> mA/μM cm<sup>2</sup>. The developed sensor exhibited notable levels of sensitivity, selectivity, stability, and repeatability, along with an extended linear range. The sensing technique was consequently employed to detect the histamine levels in packed food items like fermented food samples (cheese, tomato sauce, tomato ketchup, and soy sauce) at room temperature (25 °C). 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Nanostructured WS2@Chitosan-Modified Screen-Printed Carbon Electrodes for Efficient Amperometric Detection of Histamine.
Histamine, a pivotal chemical within certain cells of the human body, is responsible for eliciting various allergic symptoms, such as sneezing and a runny nose. In cases of allergies, where the immune system misidentifies typically harmless substances, such as certain foods or dust, as harmful, an efficient histamine sensor becomes imperative. This research introduces a novel sensing platform by employing a material comprising hydrothermally synthesized WS2 nanosheets and using this with a chitosan (CS) biopolymer on a screen-printed carbon electrode (SPE). Integrating WS2 and CS components on the SPE via drop-casting synergistically enhances conductivity and various sensor properties. This novel hybrid material combines organic CS and inorganic WS2 components applied for nonenzymatic histamine detection via differential pulse voltammetry. This study also included crystallite size determination and surface morphology assessment through characterization of the synthesized WS2 nanosheets. On the surface of the SPE, WS2 and CS were drop-casted. It is recommended that histamine be electrochemically measured on modified WS2/CS/SPE electrodes. Histamine measurements were conducted within a linear coverage of 1-100 μM, with a limit of detection of 0.0844 μM and sensitivity of 1.44 × 10-4 mA/μM cm2. The developed sensor exhibited notable levels of sensitivity, selectivity, stability, and repeatability, along with an extended linear range. The sensing technique was consequently employed to detect the histamine levels in packed food items like fermented food samples (cheese, tomato sauce, tomato ketchup, and soy sauce) at room temperature (25 °C). The findings recommend the utilization of electrochemical sensing on modified WS2/CS/SPE electrodes for accurate histamine detection.
ACS OmegaChemical Engineering-General Chemical Engineering
CiteScore
6.60
自引率
4.90%
发文量
3945
审稿时长
2.4 months
期刊介绍:
ACS Omega is an open-access global publication for scientific articles that describe new findings in chemistry and interfacing areas of science, without any perceived evaluation of immediate impact.