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IF 51.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Nature reviews. Chemistry Pub Date : 2025-01-31 DOI:10.1038/s41570-025-00688-5

Ian Churcher, Stuart Newbold, Christopher W. Murray

引用次数: 0

摘要

15年前，一项对药物分子在临床开发阶段的分析表明，三维特征的增加是更大成功的标志。现在，我们进行了类似的分析，以评估该里程碑式出版物的影响，并看看当时观察到的趋势今天是否仍然存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Fifteen years ago, an analysis of drug molecules moving through the stages of clinical development suggested that increased three-dimensional character was a marker of greater success. Now, we perform a similar analysis to evaluate the impact of that landmark publication and to see if the trends observed then still hold today.

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来源期刊

Nature reviews. Chemistry Chemical Engineering-General Chemical Engineering

CiteScore

52.80

自引率

0.80%

发文量

期刊介绍： Nature Reviews Chemistry is an online-only journal that publishes Reviews, Perspectives, and Comments on various disciplines within chemistry. The Reviews aim to offer balanced and objective analyses of selected topics, providing clear descriptions of relevant scientific literature. The content is designed to be accessible to recent graduates in any chemistry-related discipline while also offering insights for principal investigators and industry-based research scientists. Additionally, Reviews should provide the authors' perspectives on future directions and opinions regarding the major challenges faced by researchers in the field.