Ankura Singh, Malak Khalifeh, John Violanti, Rachel Zeig-Owens, Andrew C Todd, Moshe Z Shapiro, Madeline E Carwile, Christopher R Dasaro, Jiehui Li, Janette Yung, Mark R Farfel, Robert M Brackbill, James E Cone, Baozhen Qiao, Maria J Schymura, David J Prezant, Charles B Hall, Paolo Boffetta
{"title":"世贸中心暴露的执法人员与非世贸中心执法人员的死亡率比较。","authors":"Ankura Singh, Malak Khalifeh, John Violanti, Rachel Zeig-Owens, Andrew C Todd, Moshe Z Shapiro, Madeline E Carwile, Christopher R Dasaro, Jiehui Li, Janette Yung, Mark R Farfel, Robert M Brackbill, James E Cone, Baozhen Qiao, Maria J Schymura, David J Prezant, Charles B Hall, Paolo Boffetta","doi":"10.1007/s00420-025-02121-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>World Trade Center (WTC) rescue/recovery workers were exposed to materials hazardous to health. Previous studies found lower than expected mortality among WTC rescue/recovery workers when compared to general populations, possibly due to healthy worker effects, better healthcare access and/or incomparability of the groups. We compared mortality rates in WTC-exposed law enforcement officers (LEOs) with rates in LEOs employed by the Buffalo, NY, Police Department. We also compared both cohorts to the general population.</p><p><strong>Methods: </strong>Follow-up began at the later of one year after enrollment date or 1/1/2005 and ended at the earlier of death date or 12/31/2018. Analyses were restricted to ages 40-79 years (N = 11,476 WTC LEOs, N = 1668 non-WTC LEOs). We estimated standardized mortality ratios (SMRs) in each cohort using stratum-specific US mortality rates. Relative rates (RRs) and 95% CIs were estimated for the WTC vs. the Buffalo cohort using Poisson regression models adjusted for sex, race, age-group, and calendar-period.</p><p><strong>Results: </strong>185 deaths were observed in the WTC cohort and 186 in the Buffalo cohort. All-cause and cause-specific SMRs were significantly lower in the WTC cohort. Similarly, the adjusted all-cause mortality RR for the WTC vs. Buffalo cohorts was 0.30 (95% CI = 0.23-0.40). The cause-specific mortality RRs were all significantly < 1.</p><p><strong>Conclusion: </strong>We found lower overall and cause-specific mortality rates in WTC LEOs compared with both the general population and Buffalo LEOs. These results suggest that factors other than healthy worker effects, such as access to healthcare via the WTC Health Program, contribute to lower mortality rates in WTC rescue/recovery workers.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"215-221"},"PeriodicalIF":2.6000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937154/pdf/","citationCount":"0","resultStr":"{\"title\":\"Mortality in a cohort of WTC-exposed law-enforcement officers compared to non-WTC law-enforcement officers.\",\"authors\":\"Ankura Singh, Malak Khalifeh, John Violanti, Rachel Zeig-Owens, Andrew C Todd, Moshe Z Shapiro, Madeline E Carwile, Christopher R Dasaro, Jiehui Li, Janette Yung, Mark R Farfel, Robert M Brackbill, James E Cone, Baozhen Qiao, Maria J Schymura, David J Prezant, Charles B Hall, Paolo Boffetta\",\"doi\":\"10.1007/s00420-025-02121-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>World Trade Center (WTC) rescue/recovery workers were exposed to materials hazardous to health. Previous studies found lower than expected mortality among WTC rescue/recovery workers when compared to general populations, possibly due to healthy worker effects, better healthcare access and/or incomparability of the groups. We compared mortality rates in WTC-exposed law enforcement officers (LEOs) with rates in LEOs employed by the Buffalo, NY, Police Department. We also compared both cohorts to the general population.</p><p><strong>Methods: </strong>Follow-up began at the later of one year after enrollment date or 1/1/2005 and ended at the earlier of death date or 12/31/2018. Analyses were restricted to ages 40-79 years (N = 11,476 WTC LEOs, N = 1668 non-WTC LEOs). We estimated standardized mortality ratios (SMRs) in each cohort using stratum-specific US mortality rates. Relative rates (RRs) and 95% CIs were estimated for the WTC vs. the Buffalo cohort using Poisson regression models adjusted for sex, race, age-group, and calendar-period.</p><p><strong>Results: </strong>185 deaths were observed in the WTC cohort and 186 in the Buffalo cohort. All-cause and cause-specific SMRs were significantly lower in the WTC cohort. Similarly, the adjusted all-cause mortality RR for the WTC vs. Buffalo cohorts was 0.30 (95% CI = 0.23-0.40). The cause-specific mortality RRs were all significantly < 1.</p><p><strong>Conclusion: </strong>We found lower overall and cause-specific mortality rates in WTC LEOs compared with both the general population and Buffalo LEOs. These results suggest that factors other than healthy worker effects, such as access to healthcare via the WTC Health Program, contribute to lower mortality rates in WTC rescue/recovery workers.</p>\",\"PeriodicalId\":13761,\"journal\":{\"name\":\"International Archives of Occupational and Environmental Health\",\"volume\":\" \",\"pages\":\"215-221\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937154/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Archives of Occupational and Environmental Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00420-025-02121-2\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/1 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Archives of Occupational and Environmental Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00420-025-02121-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/1 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
目的:世界贸易中心(世贸中心)救援/恢复工作人员接触有害健康的材料。先前的研究发现,与一般人群相比,世贸中心救援/恢复工作人员的死亡率低于预期,可能是由于健康工作者的影响、更好的医疗保健机会和/或群体的不可比较性。我们比较了接触世贸中心的执法人员(LEOs)的死亡率与纽约州布法罗警察局雇用的LEOs的死亡率。我们还将这两个队列与一般人群进行了比较。方法:随访开始于入组日期后1年或2005年1月1日,结束于死亡日期较早或2018年12月31日。分析仅限于年龄在40-79岁之间(N = 11,476名WTC LEOs, N = 1668名非WTC LEOs)。我们使用美国分层特异性死亡率估计每个队列的标准化死亡率(SMRs)。使用泊松回归模型对性别、种族、年龄组和日历期间进行调整,估计WTC与Buffalo队列的相对比率(rr)和95% ci。结果:WTC组185例死亡,Buffalo组186例死亡。在WTC队列中,全因和病因特异性smr显著降低。同样,WTC组与Buffalo组的校正全因死亡率RR为0.30 (95% CI = 0.23-0.40)。结论:我们发现与普通人群和布法罗市LEOs相比,WTC LEOs的总体死亡率和原因特异性死亡率都较低。这些结果表明,除了健康工作者的影响外,其他因素,如通过世贸中心健康计划获得医疗保健,有助于降低世贸中心救援/恢复工作者的死亡率。
Mortality in a cohort of WTC-exposed law-enforcement officers compared to non-WTC law-enforcement officers.
Purpose: World Trade Center (WTC) rescue/recovery workers were exposed to materials hazardous to health. Previous studies found lower than expected mortality among WTC rescue/recovery workers when compared to general populations, possibly due to healthy worker effects, better healthcare access and/or incomparability of the groups. We compared mortality rates in WTC-exposed law enforcement officers (LEOs) with rates in LEOs employed by the Buffalo, NY, Police Department. We also compared both cohorts to the general population.
Methods: Follow-up began at the later of one year after enrollment date or 1/1/2005 and ended at the earlier of death date or 12/31/2018. Analyses were restricted to ages 40-79 years (N = 11,476 WTC LEOs, N = 1668 non-WTC LEOs). We estimated standardized mortality ratios (SMRs) in each cohort using stratum-specific US mortality rates. Relative rates (RRs) and 95% CIs were estimated for the WTC vs. the Buffalo cohort using Poisson regression models adjusted for sex, race, age-group, and calendar-period.
Results: 185 deaths were observed in the WTC cohort and 186 in the Buffalo cohort. All-cause and cause-specific SMRs were significantly lower in the WTC cohort. Similarly, the adjusted all-cause mortality RR for the WTC vs. Buffalo cohorts was 0.30 (95% CI = 0.23-0.40). The cause-specific mortality RRs were all significantly < 1.
Conclusion: We found lower overall and cause-specific mortality rates in WTC LEOs compared with both the general population and Buffalo LEOs. These results suggest that factors other than healthy worker effects, such as access to healthcare via the WTC Health Program, contribute to lower mortality rates in WTC rescue/recovery workers.
期刊介绍:
International Archives of Occupational and Environmental Health publishes Editorials, Review Articles, Original Articles, and Letters to the Editor. It welcomes any manuscripts dealing with occupational or ambient environmental problems, with a special interest in research at the interface of occupational health and clinical medicine. The scope ranges from Biological Monitoring to Dermatology, from Fibers and Dust to Human Toxicology, from Nanomaterials and Ultra-fine Dust to Night- and Shift Work, from Psycho-mental Distress and Burnout to Vibrations. A complete list of topics can be found on the right-hand side under For authors and editors.
In addition, all papers should be based on present-day standards and relate to:
-Clinical and epidemiological studies on morbidity and mortality
-Clinical epidemiological studies on the parameters relevant to the estimation of health risks
-Human experimental studies on environmental health effects. Animal experiments are only acceptable if relevant to pathogenic aspects.
-Methods for studying the topics mentioned above.