Kasai门静脉肠造口术：适应症和结果的回顾。

IF 1.4 3区医学 Q3 PEDIATRICS

Seminars in Pediatric Surgery Pub Date : 2024-12-01 DOI:10.1016/j.sempedsurg.2025.151476

Alyssa Stetson, Alexander Bondoc, Greg Tiao

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引用次数: 0

摘要

Kasai门肠造口术（KPE）可以为胆道闭锁（BA）儿童提供手术治疗，而无需肝移植（OLTxp）。在初始KPE失败且未达到胆道清除的情况下，可以尝试改良KPE。改良KPE最常见的适应症是复发性黄疸或复发性胆管炎，尽管它也适用于持续性黄疸或胆囊炎。结果是不同的，但最好的结果似乎是黄疸复发或有限发作的复发性胆管炎。在KPE失败的情况下，提供者必须根据患者的具体情况决定是尝试修改KPE还是继续使用OLTxp。虽然选择是多因素的，但接受改良性KPE的患者可能不会比接受单一KPE的患者有更差的长期预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Revision Kasai portoenterostomy: A review of indications and outcomes

The Kasai portoenterostomy (KPE) can provide a surgical cure for children with biliary atresia (BA), without the need for a liver transplant (OLTxp). Revision KPE can be attempted following a failed initial KPE where biliary clearance is not achieved. The most common indications for revision KPE are recurrent jaundice or recurrent cholangitis, although it has also been performed for persistent jaundice or bile lakes. Outcomes are heterogenous but the best results appear to be with recurrent jaundice or limited episodes of recurrent cholangitis. In the setting of a failed KPE, providers must make a patient-specific decision about whether to attempt revision KPE versus proceed with OLTxp. While the choice is multifactorial, patients who undergo revision KPE likely do not have worse long-term outcomes than patients who undergo a single KPE.

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来源期刊

Seminars in Pediatric Surgery PEDIATRICS-SURGERY

CiteScore

2.80

自引率

5.90%

发文量

审稿时长

>12 weeks

期刊介绍： Seminars in Pediatric Surgery provides current state-of-the-art reviews of subjects of interest to those charged with the surgical care of young patients. Each bimontly issue addresses a single topic with articles written by the experts in the field. Guest editors, all noted authorities, prepare each issue.