MDMA辅助治疗：MDMA治疗行为障碍的挑战、临床试验和未来。

IF 3.4 3区医学 Q2 CLINICAL NEUROLOGY

CNS Spectrums Pub Date : 2025-01-30 DOI:10.1017/S1092852925000057

Steve O'Brien, David Nutt

{"title":"MDMA辅助治疗：MDMA治疗行为障碍的挑战、临床试验和未来。","authors":"Steve O'Brien, David Nutt","doi":"10.1017/S1092852925000057","DOIUrl":null,"url":null,"abstract":"This chapter explores the complex and controversial path of MDMA-assisted therapy (MDMA-AT) for treating post-traumatic stress disorder (PTSD) and other behavioral disorders. It covers MDMA's history from research to recreation to medicine, the pivotal trials, and the challenges faced by researchers. Despite recent setbacks for the clinical application of MDMA, the chapter argues that it holds potential for transforming psychiatry and discusses the uncertain future amidst ongoing debates over ethics, methodology, and political influence.","PeriodicalId":10505,"journal":{"name":"CNS Spectrums","volume":" ","pages":"e15"},"PeriodicalIF":3.4000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MDMA-assisted therapy: challenges, clinical trials, and the future of MDMA in treating behavioral disorders.\",\"authors\":\"Steve O'Brien, David Nutt\",\"doi\":\"10.1017/S1092852925000057\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This chapter explores the complex and controversial path of MDMA-assisted therapy (MDMA-AT) for treating post-traumatic stress disorder (PTSD) and other behavioral disorders. It covers MDMA's history from research to recreation to medicine, the pivotal trials, and the challenges faced by researchers. Despite recent setbacks for the clinical application of MDMA, the chapter argues that it holds potential for transforming psychiatry and discusses the uncertain future amidst ongoing debates over ethics, methodology, and political influence.\",\"PeriodicalId\":10505,\"journal\":{\"name\":\"CNS Spectrums\",\"volume\":\" \",\"pages\":\"e15\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-01-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"CNS Spectrums\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1017/S1092852925000057\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"CNS Spectrums","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/S1092852925000057","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

本章探讨了mdma辅助治疗（MDMA-AT）治疗创伤后应激障碍（PTSD）和其他行为障碍的复杂和有争议的路径。它涵盖了MDMA的历史，从研究到娱乐再到医学，关键的试验，以及研究人员面临的挑战。尽管MDMA的临床应用最近遭遇挫折，但本章认为它具有改变精神病学的潜力，并讨论了正在进行的关于伦理、方法和政治影响的辩论中不确定的未来。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

MDMA-assisted therapy: challenges, clinical trials, and the future of MDMA in treating behavioral disorders.

This chapter explores the complex and controversial path of MDMA-assisted therapy (MDMA-AT) for treating post-traumatic stress disorder (PTSD) and other behavioral disorders. It covers MDMA's history from research to recreation to medicine, the pivotal trials, and the challenges faced by researchers. Despite recent setbacks for the clinical application of MDMA, the chapter argues that it holds potential for transforming psychiatry and discusses the uncertain future amidst ongoing debates over ethics, methodology, and political influence.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

CNS Spectrums 医学-精神病学

CiteScore

6.20

自引率

6.10%

发文量

239

审稿时长

>12 weeks

期刊介绍： CNS Spectrums covers all aspects of the clinical neurosciences, neurotherapeutics, and neuropsychopharmacology, particularly those pertinent to the clinician and clinical investigator. The journal features focused, in-depth reviews, perspectives, and original research articles. New therapeutics of all types in psychiatry, mental health, and neurology are emphasized, especially first in man studies, proof of concept studies, and translational basic neuroscience studies. Subject coverage spans the full spectrum of neuropsychiatry, focusing on those crossing traditional boundaries between neurology and psychiatry.