慢性肾病患者获得对比增强心血管磁共振的不公平:来自英国心血管磁共振学会的一项调查

IF 6.1 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
William E Moody, Ayisha Mehtab Khan-Kheil, Tamara Naneishvili, Lucy E Hudsmith, Gabriella Captur, Thomas A Treibel, Daniel Sado, Timothy Fairbairn, Gerry P McCann, Saul G Myerson, Colin Berry, Mark Westwood, Niall G Keenan
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引用次数: 0

摘要

目的:探讨在慢性肾脏疾病(CKD)患者中使用钆基造影剂(GBCA)进行心血管磁共振(CMR)的效果。方法:于2022年10月向英国所有CMR单位的服务主管发送电子调查,要求提供有关当前部门协议和实践的信息。结果:在调查的82个英国CMR单位中,有效率达到55%。在过去的10年里,没有肾源性系统性纤维化(NSF)的病例报道。只有不到一半的中心(45,49%中的22个)在进行对比增强CMR前常规要求患者估计肾小球滤过率(eGFR)。相反,18%(8/45)的单位不检查eGFR, 20%(9/45)的单位只要求bb0 ~ 65岁患者检查eGFR,而33%(15/45)的单位评估已知患有CKD的患者的eGFR。所有中心都使用II组gbca:大多数(36/ 45,80%)倾向于gadobutrol (Gadovist),而大多数剩余单位(8/ 45,18%)使用gadoterate meglumine (Dotarem)。五分之一的中心(9/ 45,20%)目前不为eGFR 2患者提供对比增强CMR。在为这组患者提供对比的CMR单位中,28%(10/36)没有获得肾源性系统性纤维化风险的同意。结论:英国五分之一的中心不为4期和5期CKD患者提供对比增强CMR。这一发现呼吁更新指南,以实现护理标准化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inequity of access to contrast-enhanced cardiovascular magnetic resonance in patients with chronic kidney disease: A survey from the British Society of Cardiovascular Magnetic Resonance.

Objectives: To examine the provision of cardiovascular magnetic resonance (CMR) using gadolinium-based contrast agents (GBCA) in patients with chronic kidney disease (CKD).

Methods: An electronic survey was sent to the service leads of all CMR units in the UK in October 2022 requesting information on current departmental protocols and practices.

Results: A response rate of 55% was achieved from the 82 UK CMR units surveyed. There were no known cases of nephrogenic systemic fibrosis (NSF) reported within the past 10 years. Just under half the centers (22 out of 45, 49%) routinely require an estimated glomerular filtration rate (eGFR) in patients before performing contrast-enhanced CMR. Conversely, 18% (8/45) of units do not check eGFR, 20% (9/45) only require an eGFR in patients aged >65 years, while 33% (15/45) assess eGFR in patients known to have CKD. All centers use group II GBCAs: the majority (36/45, 80%) favoring gadobutrol (Gadovist), while gadoterate meglumine (Dotarem) is used in most of the remaining units (8/45, 18%). One in five centers (9/45, 20%) do not currently offer contrast-enhanced CMR to patients with an eGFR <30 mL/min/1.73 m2. Of the CMR units that do offer contrast to this group of patients, 28% (10/36) do not obtain consent for the risk of NSF.

Conclusion: One in five centers across the UK does not offer contrast-enhanced CMR to patients with stage 4 and 5 CKD. This finding serves as a call for updated guidance with the intention of standardizing care.

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来源期刊
CiteScore
10.90
自引率
12.50%
发文量
61
审稿时长
6-12 weeks
期刊介绍: Journal of Cardiovascular Magnetic Resonance (JCMR) publishes high-quality articles on all aspects of basic, translational and clinical research on the design, development, manufacture, and evaluation of cardiovascular magnetic resonance (CMR) methods applied to the cardiovascular system. Topical areas include, but are not limited to: New applications of magnetic resonance to improve the diagnostic strategies, risk stratification, characterization and management of diseases affecting the cardiovascular system. New methods to enhance or accelerate image acquisition and data analysis. Results of multicenter, or larger single-center studies that provide insight into the utility of CMR. Basic biological perceptions derived by CMR methods.
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