慢性髓系白血病诊断中附加染色体异常的临床和预后意义

IF 10.1 1区医学 Q1 HEMATOLOGY

American Journal of Hematology Pub Date : 2025-01-28 DOI:10.1002/ajh.27608

Jiří Mayer, Petra Čičátková, Lenka Kováčová, Marie Jarošová, Michal Karas, Pavel Jindra, Hana Klamová, Kateřina Machová Poláková, Olga Černá, Eduard Cmunt, Petra Bělohlávková, Pavel Žák, Edgar Faber, Tomáš Papajík, Lukáš Stejskal, Ivana Ježíšková, Barbora Weinbergerová, Tomáš Jurček, Tomáš Horňák, Daniela Žáčková, Šárka Ransdorfová, Milena Holzerová, Tomáš Pavlík

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引用次数: 0

摘要

t（v;22）对鞋底、主干道的影响均为(+8,n = 14；+Ph, n = 10；+19, n = 1)，无进展生存期-Y。将生存曲线与标准t（9;22）易位患者进行比较。其他ACAs或复杂核型不影响生存。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Clinical and Prognostic Significance of Additional Chromosomal Abnormalities at Diagnosis of Chronic Myeloid Leukemia

查看原文本刊更多论文

Clinical and Prognostic Significance of Additional Chromosomal Abnormalities at Diagnosis of Chronic Myeloid Leukemia

The influence of t(v;22) sole, major route ACAs all (+8, n = 14; +Ph, n = 10; +19, n = 1), and -Y sole on progression-free survival. Survival curves are compared with those of patients with the standard t(9;22) translocation. Other ACAs or complex karyotypes did not influence survival.

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来源期刊

American Journal of Hematology 医学-血液学

CiteScore

15.70

自引率

3.90%

发文量

363

审稿时长

3-6 weeks

期刊介绍： The American Journal of Hematology offers extensive coverage of experimental and clinical aspects of blood diseases in humans and animal models. The journal publishes original contributions in both non-malignant and malignant hematological diseases, encompassing clinical and basic studies in areas such as hemostasis, thrombosis, immunology, blood banking, and stem cell biology. Clinical translational reports highlighting innovative therapeutic approaches for the diagnosis and treatment of hematological diseases are actively encouraged.The American Journal of Hematology features regular original laboratory and clinical research articles, brief research reports, critical reviews, images in hematology, as well as letters and correspondence.