L Ingolotti, M Bejarano, N Tamborenea, A Mercé, C Arguissain, L Martin, J Morbiducci, V Azcona, L Teplizky, E Casals, A Hernandez, M Marseillan, A Secco
{"title":"原发性Sjögren综合征患者口腔健康相关生活质量","authors":"L Ingolotti, M Bejarano, N Tamborenea, A Mercé, C Arguissain, L Martin, J Morbiducci, V Azcona, L Teplizky, E Casals, A Hernandez, M Marseillan, A Secco","doi":"10.4317/medoral.26934","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Primary Sjögren Syndrome (pSS) is an autoimmune disease that usually affects salivary glands. Research about the impact of oral health in quality of life of patients with pSS is scarce.</p><p><strong>Objectives: </strong>to describe the characteristics of oral involvement in patients with pSS; To assess quality of life related to oral health (QOL-OH); to determine association between QOL-OH and saliva production, disease activity, and damage.</p><p><strong>Material and methods: </strong>An observational, analytical and cross-sectional study was conducted. Patients aged ≥18 years with pSS were included. Primary outcome was assessed by the Oral Health Impact Profile (OHIP14sp). The EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI), the EULAR Sjögren's syndrome Disease Activity Index (ESSDAI), the Sjogren's Syndrome Damage Index (SSDI) and a Visual Analogue Scale (VAS) for xerostomia, were performed. A dentist evaluated the Decayed, Missing, and Filled Permanent Teeth index (DMFT), O'Leary index (OLI) and Loe & Silnes index (LSI). A multiple linear regression model was performed, taking OHIP14sp as the dependent variable.</p><p><strong>Results: </strong>51 patients were included. Mean age 54 (±13 years). The OHIP-14sp median was 16 [6-25], xerostomia VAS median was 60 [30-80]. Mean of ESSPRI: 4 (± 2.6), ESSDAI median: 0 [0-2], SSDDI median: 3 [2-4]. Oral involvement occurred in 100% of patients, DMFT median: 22 [14-28], OLI median: 21[13-30]. In the univariate analysis, OHIP14sp was significantly associated with ESSPRI (β2 95%CI 0.72-3.3), xerostomia VAS (β0.19 95%CI 0.08-0.29) and category 2 of the LSI (β: 18 95% CI: 5-31). In the multivariate analysis, OHIP14sp was independently and significantly associated with xerostomia VAS (β0.19 95%CI 0.09-0.29) and category 2 of LSI (β19 95% CI: 7.7-29.7).</p><p><strong>Conclusions: </strong>These findings demonstrate the effects of xerostomia on daily life of patients influencing not only their oral health but also their quality of life.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e265-e270"},"PeriodicalIF":2.1000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11972641/pdf/","citationCount":"0","resultStr":"{\"title\":\"Oral health-related quality of life in primary Sjögren's Syndrome.\",\"authors\":\"L Ingolotti, M Bejarano, N Tamborenea, A Mercé, C Arguissain, L Martin, J Morbiducci, V Azcona, L Teplizky, E Casals, A Hernandez, M Marseillan, A Secco\",\"doi\":\"10.4317/medoral.26934\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Primary Sjögren Syndrome (pSS) is an autoimmune disease that usually affects salivary glands. Research about the impact of oral health in quality of life of patients with pSS is scarce.</p><p><strong>Objectives: </strong>to describe the characteristics of oral involvement in patients with pSS; To assess quality of life related to oral health (QOL-OH); to determine association between QOL-OH and saliva production, disease activity, and damage.</p><p><strong>Material and methods: </strong>An observational, analytical and cross-sectional study was conducted. Patients aged ≥18 years with pSS were included. Primary outcome was assessed by the Oral Health Impact Profile (OHIP14sp). The EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI), the EULAR Sjögren's syndrome Disease Activity Index (ESSDAI), the Sjogren's Syndrome Damage Index (SSDI) and a Visual Analogue Scale (VAS) for xerostomia, were performed. A dentist evaluated the Decayed, Missing, and Filled Permanent Teeth index (DMFT), O'Leary index (OLI) and Loe & Silnes index (LSI). A multiple linear regression model was performed, taking OHIP14sp as the dependent variable.</p><p><strong>Results: </strong>51 patients were included. Mean age 54 (±13 years). The OHIP-14sp median was 16 [6-25], xerostomia VAS median was 60 [30-80]. Mean of ESSPRI: 4 (± 2.6), ESSDAI median: 0 [0-2], SSDDI median: 3 [2-4]. Oral involvement occurred in 100% of patients, DMFT median: 22 [14-28], OLI median: 21[13-30]. In the univariate analysis, OHIP14sp was significantly associated with ESSPRI (β2 95%CI 0.72-3.3), xerostomia VAS (β0.19 95%CI 0.08-0.29) and category 2 of the LSI (β: 18 95% CI: 5-31). In the multivariate analysis, OHIP14sp was independently and significantly associated with xerostomia VAS (β0.19 95%CI 0.09-0.29) and category 2 of LSI (β19 95% CI: 7.7-29.7).</p><p><strong>Conclusions: </strong>These findings demonstrate the effects of xerostomia on daily life of patients influencing not only their oral health but also their quality of life.</p>\",\"PeriodicalId\":49016,\"journal\":{\"name\":\"Medicina Oral Patologia Oral Y Cirugia Bucal\",\"volume\":\" \",\"pages\":\"e265-e270\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11972641/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicina Oral Patologia Oral Y Cirugia Bucal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4317/medoral.26934\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina Oral Patologia Oral Y Cirugia Bucal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4317/medoral.26934","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Oral health-related quality of life in primary Sjögren's Syndrome.
Background: Primary Sjögren Syndrome (pSS) is an autoimmune disease that usually affects salivary glands. Research about the impact of oral health in quality of life of patients with pSS is scarce.
Objectives: to describe the characteristics of oral involvement in patients with pSS; To assess quality of life related to oral health (QOL-OH); to determine association between QOL-OH and saliva production, disease activity, and damage.
Material and methods: An observational, analytical and cross-sectional study was conducted. Patients aged ≥18 years with pSS were included. Primary outcome was assessed by the Oral Health Impact Profile (OHIP14sp). The EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI), the EULAR Sjögren's syndrome Disease Activity Index (ESSDAI), the Sjogren's Syndrome Damage Index (SSDI) and a Visual Analogue Scale (VAS) for xerostomia, were performed. A dentist evaluated the Decayed, Missing, and Filled Permanent Teeth index (DMFT), O'Leary index (OLI) and Loe & Silnes index (LSI). A multiple linear regression model was performed, taking OHIP14sp as the dependent variable.
Results: 51 patients were included. Mean age 54 (±13 years). The OHIP-14sp median was 16 [6-25], xerostomia VAS median was 60 [30-80]. Mean of ESSPRI: 4 (± 2.6), ESSDAI median: 0 [0-2], SSDDI median: 3 [2-4]. Oral involvement occurred in 100% of patients, DMFT median: 22 [14-28], OLI median: 21[13-30]. In the univariate analysis, OHIP14sp was significantly associated with ESSPRI (β2 95%CI 0.72-3.3), xerostomia VAS (β0.19 95%CI 0.08-0.29) and category 2 of the LSI (β: 18 95% CI: 5-31). In the multivariate analysis, OHIP14sp was independently and significantly associated with xerostomia VAS (β0.19 95%CI 0.09-0.29) and category 2 of LSI (β19 95% CI: 7.7-29.7).
Conclusions: These findings demonstrate the effects of xerostomia on daily life of patients influencing not only their oral health but also their quality of life.
期刊介绍：
1. Oral Medicine and Pathology:
Clinicopathological as well as medical or surgical management aspects of
diseases affecting oral mucosa, salivary glands, maxillary bones, as well as
orofacial neurological disorders, and systemic conditions with an impact on
the oral cavity.
2. Oral Surgery:
Surgical management aspects of diseases affecting oral mucosa, salivary glands,
maxillary bones, teeth, implants, oral surgical procedures. Surgical management
of diseases affecting head and neck areas.
3. Medically compromised patients in Dentistry:
Articles discussing medical problems in Odontology will also be included, with
a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients.
4. Implantology
5. Periodontology
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