以SiO2、Y2O3和Al2O3为助烧结剂增强氮化硅陶瓷的力学性能和体外生物活性。

IF 3.3 2区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2025-01-20 DOI:10.1016/j.jmbbm.2025.106901

Yongning Han , Wenying Zhou , Jian Li , Zhuoqun Han , Lunan Bi , Zheng Zhang , Yang Wang , Ling Li , Degang Zhao

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引用次数: 0

摘要

氮化硅（Si₃N₄）陶瓷具有优异的机械性能和生物相容性，使其非常适合生物医学应用，特别是在植入物中。在这项研究中，研究了不同数量的Y₂O₃-Al₂O₃-SiO₂助烧结剂对Si₃N₄陶瓷的力学性能和生物活性的影响。将烧结添加剂的含量从4 wt%增加到8 wt%，大大提高了陶瓷的体积密度，从而显著提高了机械性能。这些变化包括维氏硬度增加到10.07 GPa，抗弯强度增加到605 MPa，断裂韧性增加到2.43 MPa m1/2。烧结添加量为8wt %时，由于高长宽比和低孔隙率，获得了最佳的力学性能组合。在模拟体液（SBF）中浸泡后，Si₃N₄陶瓷表面涂有一层形态类似于羟基磷灰石的富Ca和p层。sio2的存在促进了羟基磷灰石的成核和生长，Ca2 +离子的快速释放和磷灰石层的持续稳定。

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Enhanced mechanical properties and in vitro bioactivity of silicon nitride ceramics with SiO2, Y2O3, and Al2O3 as sintering aids

Silicon nitride (Si₃N₄) ceramics exhibit excellent mechanical properties and biocompatibility, making them highly suitable for biomedical applications, particularly in implants. In this study, the mechanical properties and bioactivity of Si₃N₄ ceramics with varying amounts of Y₂O₃-Al₂O₃-SiO₂ sintering aids were investigated. Increasing the sintering additive content from 4 wt% to 8 wt% substantially improved the bulk density of the ceramics, leading to notable enhancements in mechanical properties. These included a Vickers hardness increase to 10.07 GPa, a flexural strength increase to 605 MPa, and a fracture toughness increase to 2.43 MPa m^1/2. The optimal combination of mechanical properties was achieved with 8 wt% sintering additives due to the higher aspect ratio and lower porosity. After immersion in simulated body fluid (SBF), the surface of the Si₃N₄ ceramics was coated with a Ca and P-rich layer, morphologically similar to hydroxyapatite. The layer formation was facilitated by the presence of SiO₂, which promoted hydroxyapatite nucleation and growth, as well as the rapid release of Ca²⁺ ions and the sustained stability of the apatite layer.

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来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.