子宫-胎盘对猪宫内生长限制的适应。

IF 1.9 2区农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Domestic animal endocrinology Pub Date : 2025-01-16 DOI:10.1016/j.domaniend.2025.106917

Morgan S. Clemens , Maria F. Tyree , Claire Stenhouse

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引用次数: 0

摘要

宫内生长受限（IUGR）是猪的一种常见疾病，与仔猪的高死亡率和发病率有关，发生在妊娠早期。这篇综述文章探讨了IUGR胎儿在不同妊娠阶段与正常产仔相比子宫和胎盘组织的差异。具体来说，我们将回顾迄今为止可用的知识，描述与IUGR胎儿妊娠相关的子宫内膜和胎盘组织的差异：1)结构，2)细胞凋亡和增殖，3)粘连，以及4)血管生成。提高对IUGR调节机制的理解对于制定策略以最大限度地减少IUGR对猪养殖的影响至关重要，从而提高繁殖效率和动物福利。

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Utero-placental adaptations in response to intrauterine growth restriction in swine

Intrauterine growth restriction (IUGR) is a common condition in swine associated with high piglet mortality and morbidity that develops in early gestation. This review article explores differences in uterine and placental tissues associated with IUGR fetuses compared to their normally-grown littermates at different stages of gestation. Specifically, we will review the available knowledge to date describing differences in 1) structure, 2) cellular apoptosis and proliferation, 3) adhesion, and 4) angiogenesis in endometrial and placental tissues associated with IUGR fetuses across gestation. Improved understanding of the mechanisms regulating IUGR is essential for the development of strategies to minimize the impact of IUGR in swine operations, thus improving reproductive efficiency and animal welfare.

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来源期刊

Domestic animal endocrinology 农林科学-奶制品与动物科学

CiteScore

5.50

自引率

4.80%

发文量

审稿时长

31 days

期刊介绍： Domestic Animal Endocrinology publishes scientific papers dealing with the study of the endocrine physiology of domestic animal species. Those manuscripts utilizing other species as models for clinical or production problems associated with domestic animals are also welcome. Topics covered include: Classical and reproductive endocrinology- Clinical and applied endocrinology- Regulation of hormone secretion- Hormone action- Molecular biology- Cytokines- Growth factors