老年妇女是否可以选择立即乳房重建?老年人口与青年人口的比较研究。

IF 2.9 3区 医学 Q2 ONCOLOGY
Julie Marcadet, Caroline Bouche, Carlo Arellano, Elodie Gauroy, Mony Ung, Eva Jouve, Gabrielle Selmes, Marc Soule-Tholy, Thomas Meresse, Carole Massabeau, Ana Cavillon, Charlotte Vaysse
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引用次数: 0

摘要

目的:比较老年患者(EP)与年轻患者(YP)在全乳切除术(TM)后立即乳房重建(IBR)术后并发症(POC)的发生率。方法:这项回顾性研究纳入了2014年1月至2022年5月在图卢兹-奥科普勒癌症研究所(IUCT-O)接受治疗的患者。主要观察指标为术后30天内POC的发生率。次要结局包括开始辅助治疗前的延迟和再住院率。结果:老年患者的POC发生率明显高于年轻患者,EP发生率为27.9%,YP发生率仅为14.8%。然而,并发症的严重程度在YP和EP之间没有显著差异(YP占主要POC的69.1%,EP占64.7%,P = 0.6680)。两组患者30天内再住院率相似(YP 67.3%, EP 61.8%, P = 0.5962)。最重要的是,与年轻人群相比,这些并发症不会导致开始辅助治疗的延迟。年龄≥70岁和肥胖(BMI≥30)被确定为POC的独立危险因素。结论:尽管老年患者POC发生率较高,但可考虑立即进行乳房重建,但术前应谨慎选择和评估患者,以限制POC的发生风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is Immediate Breast Reconstruction an Option for Elderly Women? A Comparative Study Between Elderly and Younger Population.

Objective: To evaluate the incidence of postoperative complications (POC) in elderly patients (EP) compared to younger patients (YP) following immediate breast reconstruction (IBR) after total mastectomy (TM).

Methods: This retrospective study included patients treated at the Institut Universitaire of Cancer of Toulouse-Oncopole (IUCT-O) between January 2014 and May 2022. The primary outcome was the incidence of POC within 30 days postoperatively. Secondary outcomes included the delay before initiation of adjuvant treatments and re-hospitalization rates.

Results: Elderly patients had a significantly higher rate of POC compared to younger patients, affecting 27.9% of EP and only 14.8% of YP. However, the severity of complications does not differ significantly between YP and EP (69.1% of major POC for YP and 64.7% for EP, P = .6680). Rates of re-hospitalization within 30 days between the 2 groups are similar (67.3% for YP and 61.8% for EP, P = .5962). Most importantly, these complications are not responsible for a delay in initiating adjuvant treatment compared with the younger population. Age ≥ 70 years and obesity (BMI ≥ 30) were identified as independent risk factors for POC.

Conclusion: Despite a higher rate of POC, immediate breast reconstruction can be considered for elderly patients, but these patients should be carefully selected and assessed preoperatively to limit the risk of POC.

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来源期刊
Clinical breast cancer
Clinical breast cancer 医学-肿瘤学
CiteScore
5.40
自引率
3.20%
发文量
174
审稿时长
48 days
期刊介绍: Clinical Breast Cancer is a peer-reviewed bimonthly journal that publishes original articles describing various aspects of clinical and translational research of breast cancer. Clinical Breast Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of breast cancer. The main emphasis is on recent scientific developments in all areas related to breast cancer. Specific areas of interest include clinical research reports from various therapeutic modalities, cancer genetics, drug sensitivity and resistance, novel imaging, tumor genomics, biomarkers, and chemoprevention strategies.
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