{"title":"坦桑尼亚北部乞力马扎罗山基督教医疗中心耳鼻喉科患者的变应性鼻炎及其相关并发症:横断面研究","authors":"Kenneth Mlay, Gasper Temba, Adrian Matasha, Pendael Mzonge, Denis Katundu, Desderius Chussi","doi":"10.1002/iid3.70130","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Introduction</h3>\n \n <p>Allergic rhinitis is the specific inflammation against allergen by immune defense cells on the nasal mucosa, which can lead to chronic nasal symptoms such as sneezing, itching, runny nose, and nasal congestion. It is associated with high morbidity including sinusitis, asthma, otitis media, hypertrophied inferior turbinate, and nasal polyps. Despite its complications, it remains poorly recognized and tracked.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A cross-sectional hospital-based study was done, a total of 221 patients received Ear, Nose And Throat services at Kilimanjaro Christian Medical Center during the study period all patients with a clinical diagnosis of allergic rhinitis were captured; Data was collected using a pre-tested coded questionnaire (Score For Allergic Rhinitis). The data was then analyzed using SPSS version 22.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>A total of 221 patients with a clinical diagnosis of allergic rhinitis were approached in a 6 months study period, 111 (50.2%) were females, and 140 (63.4%) were residing in urban areas. The prevalence of allergic rhinitis was 23.9%. Factors such as age OR 0.12, 95% CI (0.03; 0.40), education OR 0.13, 95% CI (0.04; 0.44), occupation OR 3.75, 95% CI (1.36; 10.32), adenotonsillar hypertrophy OR 4.66, 95% CI (2.21; 9.80), and OME OR 4.11, 95% CI (1.32; 12.83) (<i>p</i> = 0.009) were found to be significantly associated with allergic rhinitis. 60.4%, Inferior turbinate hypertrophy is the leading co-morbidity of allergic rhinitis which accounts for 64.7%.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Allergic rhinitis is among the common health problems affecting Tanzanians. It is a commonly seen disorder in younger age ( < 15 years) which is in correlation with other studies done in Africa and worldwide.</p>\n </section>\n </div>","PeriodicalId":13289,"journal":{"name":"Immunity, Inflammation and Disease","volume":"13 1","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760977/pdf/","citationCount":"0","resultStr":"{\"title\":\"Allergic Rhinitis and Its Associated Co-Morbidities Among Patients Attending the ENT Department at Kilimanjaro Christian Medical Center in Northern Tanzania: Cross-Sectional Study\",\"authors\":\"Kenneth Mlay, Gasper Temba, Adrian Matasha, Pendael Mzonge, Denis Katundu, Desderius Chussi\",\"doi\":\"10.1002/iid3.70130\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Introduction</h3>\\n \\n <p>Allergic rhinitis is the specific inflammation against allergen by immune defense cells on the nasal mucosa, which can lead to chronic nasal symptoms such as sneezing, itching, runny nose, and nasal congestion. It is associated with high morbidity including sinusitis, asthma, otitis media, hypertrophied inferior turbinate, and nasal polyps. Despite its complications, it remains poorly recognized and tracked.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A cross-sectional hospital-based study was done, a total of 221 patients received Ear, Nose And Throat services at Kilimanjaro Christian Medical Center during the study period all patients with a clinical diagnosis of allergic rhinitis were captured; Data was collected using a pre-tested coded questionnaire (Score For Allergic Rhinitis). The data was then analyzed using SPSS version 22.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>A total of 221 patients with a clinical diagnosis of allergic rhinitis were approached in a 6 months study period, 111 (50.2%) were females, and 140 (63.4%) were residing in urban areas. The prevalence of allergic rhinitis was 23.9%. Factors such as age OR 0.12, 95% CI (0.03; 0.40), education OR 0.13, 95% CI (0.04; 0.44), occupation OR 3.75, 95% CI (1.36; 10.32), adenotonsillar hypertrophy OR 4.66, 95% CI (2.21; 9.80), and OME OR 4.11, 95% CI (1.32; 12.83) (<i>p</i> = 0.009) were found to be significantly associated with allergic rhinitis. 60.4%, Inferior turbinate hypertrophy is the leading co-morbidity of allergic rhinitis which accounts for 64.7%.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Allergic rhinitis is among the common health problems affecting Tanzanians. 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引用次数: 0
摘要
简介:变应性鼻炎是鼻黏膜上免疫防御细胞对过敏原的特异性炎症反应,可导致慢性鼻部症状,如打喷嚏、瘙痒、流鼻涕、鼻塞等。它的高发病率包括鼻窦炎、哮喘、中耳炎、下鼻甲肥大和鼻息肉。尽管它很复杂,但人们对它的认识和追踪仍然很差。方法:以医院为基础的横断面研究,在研究期间,共有221例患者在乞力马扎罗山基督教医疗中心接受耳鼻喉科治疗,所有临床诊断为变应性鼻炎的患者均被捕获;使用预测试的编码问卷(过敏性鼻炎评分)收集数据。然后使用SPSS version 22对数据进行分析。结果:在6个月的研究期间,共有221例临床诊断为变应性鼻炎的患者就诊,其中女性111例(50.2%),城市居民140例(63.4%)。变应性鼻炎患病率为23.9%。年龄等因素OR 0.12, 95% CI (0.03;0.40),教育OR 0.13, 95% CI (0.04;0.44),职业OR 3.75, 95% CI (1.36;10.32),腺扁桃体肥大OR 4.66, 95% CI (2.21;9.80), OME OR 4.11, 95% CI (1.32;12.83) (p = 0.009)与变应性鼻炎显著相关。下鼻甲肥大是变应性鼻炎的主要合并症,占64.7%。结论:变应性鼻炎是坦桑尼亚人常见的健康问题之一。这是一种常见于年轻人的疾病(
Allergic Rhinitis and Its Associated Co-Morbidities Among Patients Attending the ENT Department at Kilimanjaro Christian Medical Center in Northern Tanzania: Cross-Sectional Study
Introduction
Allergic rhinitis is the specific inflammation against allergen by immune defense cells on the nasal mucosa, which can lead to chronic nasal symptoms such as sneezing, itching, runny nose, and nasal congestion. It is associated with high morbidity including sinusitis, asthma, otitis media, hypertrophied inferior turbinate, and nasal polyps. Despite its complications, it remains poorly recognized and tracked.
Methods
A cross-sectional hospital-based study was done, a total of 221 patients received Ear, Nose And Throat services at Kilimanjaro Christian Medical Center during the study period all patients with a clinical diagnosis of allergic rhinitis were captured; Data was collected using a pre-tested coded questionnaire (Score For Allergic Rhinitis). The data was then analyzed using SPSS version 22.
Results
A total of 221 patients with a clinical diagnosis of allergic rhinitis were approached in a 6 months study period, 111 (50.2%) were females, and 140 (63.4%) were residing in urban areas. The prevalence of allergic rhinitis was 23.9%. Factors such as age OR 0.12, 95% CI (0.03; 0.40), education OR 0.13, 95% CI (0.04; 0.44), occupation OR 3.75, 95% CI (1.36; 10.32), adenotonsillar hypertrophy OR 4.66, 95% CI (2.21; 9.80), and OME OR 4.11, 95% CI (1.32; 12.83) (p = 0.009) were found to be significantly associated with allergic rhinitis. 60.4%, Inferior turbinate hypertrophy is the leading co-morbidity of allergic rhinitis which accounts for 64.7%.
Conclusion
Allergic rhinitis is among the common health problems affecting Tanzanians. It is a commonly seen disorder in younger age ( < 15 years) which is in correlation with other studies done in Africa and worldwide.
期刊介绍:
Immunity, Inflammation and Disease is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research across the broad field of immunology. Immunity, Inflammation and Disease gives rapid consideration to papers in all areas of clinical and basic research. The journal is indexed in Medline and the Science Citation Index Expanded (part of Web of Science), among others. It welcomes original work that enhances the understanding of immunology in areas including:
• cellular and molecular immunology
• clinical immunology
• allergy
• immunochemistry
• immunogenetics
• immune signalling
• immune development
• imaging
• mathematical modelling
• autoimmunity
• transplantation immunology
• cancer immunology