{"title":"体外逐渐直径取栓支架的分析。","authors":"Caifeng Shen, Zhenjian Ma, Hong Li, Ming Wei","doi":"10.1515/tnsci-2022-0351","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To analyze the effect of gradient thrombectomy stent <i>in vitro</i>.</p><p><strong>Methods: </strong>The cerebrovascular fluid circulation model was made and fixed on the test table. About 0.9% sodium chloride injection was injected to the vascular model through a miniature water pump to circulate it. Four kinds of thrombus products containing different red blood cell (RBC) volumes of 0, 5, 40, and 80% were placed at the target location as thrombus. Each type of thrombus was removed five times using SOLITAIRE stent and gradient thrombectomy stent. The thrombectomy effects were observed by comparison of the two types of stents.</p><p><strong>Results: </strong>Thrombus containing 80% volume of RBC escaped thrombus fragments during thrombectomy with both stents. Thrombus containing 0% volume of RBC (rich in fibrin) had poor chimerism with stents. In the thrombus containing 0% RBC volume, there was no statistically significant difference between the two stents (<i>p</i> = 1). Thrombus removal was successful in all cases.</p><p><strong>Conclusion: </strong>The gradient thrombectomy stent is as effective as the currently used thrombectomy stent <i>in vitro</i> studies, and there is much room for improvement.</p>","PeriodicalId":23227,"journal":{"name":"Translational Neuroscience","volume":"16 1","pages":"20220351"},"PeriodicalIF":1.8000,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751670/pdf/","citationCount":"0","resultStr":"{\"title\":\"Analysis of gradual diameter thrombectomy stent <i>in vitro</i>.\",\"authors\":\"Caifeng Shen, Zhenjian Ma, Hong Li, Ming Wei\",\"doi\":\"10.1515/tnsci-2022-0351\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To analyze the effect of gradient thrombectomy stent <i>in vitro</i>.</p><p><strong>Methods: </strong>The cerebrovascular fluid circulation model was made and fixed on the test table. About 0.9% sodium chloride injection was injected to the vascular model through a miniature water pump to circulate it. Four kinds of thrombus products containing different red blood cell (RBC) volumes of 0, 5, 40, and 80% were placed at the target location as thrombus. Each type of thrombus was removed five times using SOLITAIRE stent and gradient thrombectomy stent. The thrombectomy effects were observed by comparison of the two types of stents.</p><p><strong>Results: </strong>Thrombus containing 80% volume of RBC escaped thrombus fragments during thrombectomy with both stents. Thrombus containing 0% volume of RBC (rich in fibrin) had poor chimerism with stents. In the thrombus containing 0% RBC volume, there was no statistically significant difference between the two stents (<i>p</i> = 1). Thrombus removal was successful in all cases.</p><p><strong>Conclusion: </strong>The gradient thrombectomy stent is as effective as the currently used thrombectomy stent <i>in vitro</i> studies, and there is much room for improvement.</p>\",\"PeriodicalId\":23227,\"journal\":{\"name\":\"Translational Neuroscience\",\"volume\":\"16 1\",\"pages\":\"20220351\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-01-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751670/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Translational Neuroscience\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1515/tnsci-2022-0351\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1515/tnsci-2022-0351","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Analysis of gradual diameter thrombectomy stent in vitro.
Objective: To analyze the effect of gradient thrombectomy stent in vitro.
Methods: The cerebrovascular fluid circulation model was made and fixed on the test table. About 0.9% sodium chloride injection was injected to the vascular model through a miniature water pump to circulate it. Four kinds of thrombus products containing different red blood cell (RBC) volumes of 0, 5, 40, and 80% were placed at the target location as thrombus. Each type of thrombus was removed five times using SOLITAIRE stent and gradient thrombectomy stent. The thrombectomy effects were observed by comparison of the two types of stents.
Results: Thrombus containing 80% volume of RBC escaped thrombus fragments during thrombectomy with both stents. Thrombus containing 0% volume of RBC (rich in fibrin) had poor chimerism with stents. In the thrombus containing 0% RBC volume, there was no statistically significant difference between the two stents (p = 1). Thrombus removal was successful in all cases.
Conclusion: The gradient thrombectomy stent is as effective as the currently used thrombectomy stent in vitro studies, and there is much room for improvement.
期刊介绍：
Translational Neuroscience provides a closer interaction between basic and clinical neuroscientists to expand understanding of brain structure, function and disease, and translate this knowledge into clinical applications and novel therapies of nervous system disorders.
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