免疫功能低下患者的儿科骨髓成像。

IF 2.1 3区 医学 Q2 PEDIATRICS
Pediatric Radiology Pub Date : 2025-04-01 Epub Date: 2025-01-23 DOI:10.1007/s00247-024-06153-7
Sara I Sirvent Cerdá, Inés Solís Muñiz, Elena García Esparza
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引用次数: 0

摘要

免疫功能低下患者的骨髓可能由于潜在疾病、不良治疗效果和/或任何来源引起的并发症而出现异常。这种复杂性给诊断带来了重大挑战,特别是在儿童中。磁共振成像(MRI)是评估这些患者骨髓的首选方式。MRI研究的高软组织对比可以详细评估骨髓成分,包括脂肪含量、细胞结构和血管化。在生命的早期,骨髓经历了生理成熟,表现为广泛的MRI发现。了解这一发展阶段最常见的MRI特征是至关重要的。然而,同样重要的是要认识到可以模仿病理变化的生理变化,因为区分变化和真正的病理异常对于准确诊断和管理至关重要。这篇文章回顾了正常骨髓及其在儿童时期的变化,以及免疫功能低下患者中最常见的改变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Imaging paediatric bone marrow in immunocompromised patients.

The bone marrow of immunocompromised patients may exhibit abnormalities due to the underlying disease, adverse treatment effects, and/or complications arising from either source. Such complexity poses a significant diagnostic challenge, particularly in children. Magnetic resonance imaging (MRI) is the modality of choice when evaluating bone marrow in these patients. The high soft tissue contrast of MRI studies allows for detailed evaluation of bone marrow composition, including fat content, cellularity, and vascularisation. During the early years of life, bone marrow undergoes physiological maturation manifesting as a wide range of MRI findings. Understanding the most common MRI features during this phase of development is essential. However, it is equally critical to recognise physiological variations that can mimic pathological changes, as distinguishing between variations and truly pathological abnormalities is crucial for accurate diagnosis and management. This article reviews normal bone marrow and its variations during childhood, as well as the most common alterations presenting in immunocompromised patients.

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来源期刊
Pediatric Radiology
Pediatric Radiology 医学-核医学
CiteScore
4.40
自引率
17.40%
发文量
300
审稿时长
3-6 weeks
期刊介绍: Official Journal of the European Society of Pediatric Radiology, the Society for Pediatric Radiology and the Asian and Oceanic Society for Pediatric Radiology Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, complemented by reviews that set out the present state of knowledge in a particular area of the specialty or summarize specific topics in which discussion has led to clear conclusions. Advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques are described. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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