心脏和主血管漩涡血流最佳通道形状的参数化搜索。

IF 0.8 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Ya. E. Zharkov, A. V. Agafonov, Alex. Y. Gorodkov, L. A. Bockeria
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引用次数: 0

摘要

本文采用数值参数方法研究了纵向-径向剖面为zRN = Const、底部为球形穹顶的通道内的流动结构。这项研究的目的是根据轮廓的N指数和穹顶的高度来检查这些通道中的流动结构,以确定提供最佳向心旋转流动的条件,类似于心脏腔和主要血管中的血液流动。本研究分两个阶段对河道构型zRN = Const中的水流结构进行了对比分析。在第一阶段,收敛参数N从1.25变化到2.75,以确定保证最优流动条件的值。在第二阶段,对于已确定的N值,圆顶高度从2.5到15毫米不等,以确定其存在的有益影响。研究方法涉及稳态状态下的数值模拟。对收敛参数影响的研究结果表明,zR2 = Const型线为形成比损失最小、速度梯度分布均匀的旋流提供了最优条件。该通道构型与Burgers涡的解析解也表现出最佳的一致性,证实了其在静态近似流动中的有效性。对圆屋顶高度的参数化研究表明,当圆屋顶高度为7 mm时,向心旋流尺度的优化增强有助于平滑速度梯度,减少粘性损失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Parametric Search for Optimal Channel Shape for Swirling Blood Flow in the Heart and Main Vessels

The study presents a numerical parametric investigation of flow structures in channels with a longitudinal-radial profile zRN = Const and a spherical dome at the base. The goal of the study was to examine the flow structures in these channels depending on the exponent N of the profile and the height of the dome, to determine the conditions that provide optimal centripetal swirling flow, analogous to blood flow in the heart chambers and major vessels. The investigation was conducted using a comparative analysis of flow structures in channel configurations zRN = Const, carried out in two stages. In the first stage, the convergence parameter N was varied from 1.25 to 2.75 to identify the value that ensures optimal flow conditions. In the second stage, for the established value of N, the dome height was varied from 2.5 to 15 mm to identify the beneficial effects associated with its presence. The method of investigation involved numerical modeling in a steady-state regime. The results of the study on the influence of the convergence parameter revealed that the profile zR2 = Const provides optimal conditions for the formation of swirling flow with minimal specific losses and a uniform distribution of velocity gradients. This channel configuration also showed the best agreement with the analytical solutions for Burgers’ vortex, confirming its effectiveness in the static approximation of flows. The parametric investigation of dome height indicated that an optimal dome height of 7 mm contributes to the smoothing of velocity gradients and the reduction of viscous losses due to the optimal enhancement of the centripetal swirling flow scale.

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来源期刊
Doklady Biochemistry and Biophysics
Doklady Biochemistry and Biophysics 生物-生化与分子生物学
CiteScore
1.60
自引率
12.50%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Doklady Biochemistry and Biophysics is a journal consisting of English translations of articles published in Russian in biochemistry and biophysics sections of the Russian-language journal Doklady Akademii Nauk. The journal''s goal is to publish the most significant new research in biochemistry and biophysics carried out in Russia today or in collaboration with Russian authors. The journal accepts only articles in the Russian language that are submitted or recommended by acting Russian or foreign members of the Russian Academy of Sciences. The journal does not accept direct submissions in English.
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