基于相位梯度力的光学阵列分选器

IF 3.5 2区 物理与天体物理 Q2 PHYSICS, APPLIED
Yixuan Wu, Yu Liu, Shaohua Tao
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引用次数: 0

摘要

微粒分选对于生物医学、环境监测和生物芯片技术的应用至关重要。然而,传统的光学分选方法往往依赖于外部设备,如微流体装置。本文提出了一种基于相位梯度力的光学阵列分选(POAS)方案,该方案根据粒子的物理特性,通过调节相位梯度力来实现粒子的精确输送和分选。该方法集颗粒输送和分选功能于一体,无需外部辅助设备。基于POAS方案,采用复幅波束整形算法设计了相位梯度力可控的1 × 2阵列分选波束。利用阵列分选束对两种不同大小的粒子进行实验分选,先将粒子输送到指定的分选节点,再进行精确分选。分选光束的所有参数都是可调的,大大提高了光学分选技术的灵活性和可扩展性。该研究为高通量颗粒分选提供了一种替代方案,该方案可以很容易地集成到光学分选芯片中,用于医疗检测和药物输送。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Phase-gradient force-based optical array sorter
Microparticle sorting is crucial for applications in biomedicine, environmental monitoring, and biochip technology. However, traditional optical sorting methods often rely on external equipment, such as microfluidic devices. In this Letter, we proposed a phase-gradient force-based optical array sorting (POAS) scheme, which achieves the accurate transporting and sorting of the particles by regulating the phase-gradient force based on the physical characteristics of the particles. The method combines the function of particle transporting and sorting, eliminating the need for external auxiliary equipment. Based on the POAS scheme, we used the complex amplitude beam shaping algorithms to design a 1 × 2 array sorting beam with the controllable phase-gradient forces. The array sorting beam was used to experimentally sort two kinds of particles with different sizes, and the particles are first transported and then precisely sorted at the designated sorting nodes. All the parameters of the sorting beam were adjustable, which greatly enhances the flexibility and scalability of the optical sorting technology. This study provides an alternative scheme for the high-throughput particle sorting, which can be easily integrated into the optical sorting chips for applications in medical detection and drug delivery.
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来源期刊
Applied Physics Letters
Applied Physics Letters 物理-物理:应用
CiteScore
6.40
自引率
10.00%
发文量
1821
审稿时长
1.6 months
期刊介绍: Applied Physics Letters (APL) features concise, up-to-date reports on significant new findings in applied physics. Emphasizing rapid dissemination of key data and new physical insights, APL offers prompt publication of new experimental and theoretical papers reporting applications of physics phenomena to all branches of science, engineering, and modern technology. In addition to regular articles, the journal also publishes invited Fast Track, Perspectives, and in-depth Editorials which report on cutting-edge areas in applied physics. APL Perspectives are forward-looking invited letters which highlight recent developments or discoveries. Emphasis is placed on very recent developments, potentially disruptive technologies, open questions and possible solutions. They also include a mini-roadmap detailing where the community should direct efforts in order for the phenomena to be viable for application and the challenges associated with meeting that performance threshold. Perspectives are characterized by personal viewpoints and opinions of recognized experts in the field. Fast Track articles are invited original research articles that report results that are particularly novel and important or provide a significant advancement in an emerging field. Because of the urgency and scientific importance of the work, the peer review process is accelerated. If, during the review process, it becomes apparent that the paper does not meet the Fast Track criterion, it is returned to a normal track.
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