食管狭窄的不寻常原因

IF 23 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY
Gut Pub Date : 2025-01-22 DOI:10.1136/gutjnl-2025-334729
Ya-Qi Gao, Jian-Chen Fang, Yun Cui, Jing-Yuan Fang, Dan-Feng Sun
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引用次数: 0

摘要

一位57岁的女性,因反复出现的吞咽困难和吞咽困难而到胃肠科就诊约5年。她还报告了5年口腔疼痛和多重慢性口腔溃疡史,在当地医院未经活检诊断为扁平苔藓,并间歇性使用类固醇治疗。在过去五年中,她接受了三次上消化道内窥镜检查。每次内镜检查均发现食管上部轻度狭窄伴糜烂或红斑。组织学结果以炎症为主。她接受了根除幽门螺杆菌的治疗,并开了质子泵抑制剂,但她的症状仍然存在。体格检查除轻度口腔糜烂外,无明显异常。她的皮肤完好无损,没有明显的损伤。在我院再次行上消化道内镜检查,发现食管近三分之一处黏膜发白,轻度狭窄(图1A-B)。剥离……
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An unusual cause of oesophageal stricture
A 57-year-old woman presented to the Gastrointestinal Department with recurrent odynophagia and dysphagia for about 5 years. She also reported a 5-year history of oral soreness and multiple chronic oral ulcers, which were empirically diagnosed with lichen planus without biopsy in a local hospital and treated with steroids intermittently. She underwent upper gastrointestinal endoscopy three times during the last 5 years. Each endoscopy revealed mild stricture in the upper oesophagus with erosions or erythema. Histology results showed mainly inflammation. She was treated for Helicobacter pylori eradication and prescribed with proton pump inhibitors, but her symptoms remained. The physical examination was unremarkable except for mild oral erosions. Her skin was intact, without apparent lesions. Upper gastrointestinal endoscopy was performed again in our hospital, which revealed a whitish mucosa with mild stricture in the proximal third of the oesophagus (figure 1A–B). Stripping of …
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来源期刊
Gut
Gut 医学-胃肠肝病学
CiteScore
45.70
自引率
2.40%
发文量
284
审稿时长
1.5 months
期刊介绍: Gut is a renowned international journal specializing in gastroenterology and hepatology, known for its high-quality clinical research covering the alimentary tract, liver, biliary tree, and pancreas. It offers authoritative and current coverage across all aspects of gastroenterology and hepatology, featuring articles on emerging disease mechanisms and innovative diagnostic and therapeutic approaches authored by leading experts. As the flagship journal of BMJ's gastroenterology portfolio, Gut is accompanied by two companion journals: Frontline Gastroenterology, focusing on education and practice-oriented papers, and BMJ Open Gastroenterology for open access original research.
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