{"title":"周围神经阻滞联合小剂量全身麻醉在老年髋关节置换术中的应用。","authors":"Yulin Liu, Ying Zhu, Hong Fu","doi":"10.29271/jcpsp.2025.01.76","DOIUrl":null,"url":null,"abstract":"<p><p>The study assessed the effectiveness and safety of nerve block combined with low-dose general anaesthesia in elderly hip arthroplasty patients, conducted by a meta-analysis of RCTs. Six trials involving 403 patients were identified from databases such as Cochrane, MEDLINE, and PubMed. The results demonstrated a statistically significant difference in pain scores at postoperative 12hours (95% CI, -2.39 to -0.35, p = 0.008) and 24hours (95% CI, -1.86 to -0.50, p = 0.0007). Nerve block in combination with general anaesthesia holds a significant advantage over conventional general anaesthesia regarding perioperative opioid consumption (95% CI, -38.32 to -7.48, p = 0.004). This combined approach was superior in reducing the incidence of complications (95% CI, 0.11 to 0.55, p = 0.0007). However, between the two groups, there was no statistically significant difference in the 48hour pain score (95% CI, -2.58 to 0.62, p = 0.23). Essentially, this approach effectively reduces early post-surgical pain and it minimises anaesthetic use, whilst simultaneously lowering the risk of complications. Key Words: Nerve block, Elderly patients, Hip arthroplasty, Pain, Postoperative complication.</p>","PeriodicalId":94116,"journal":{"name":"Journal of the College of Physicians and Surgeons--Pakistan : JCPSP","volume":"35 1","pages":"76-82"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Peripheral Nerve Block Combined with Low-Dose General Anaesthesia in Elderly Patients Receiving Hip Arthroplasty.\",\"authors\":\"Yulin Liu, Ying Zhu, Hong Fu\",\"doi\":\"10.29271/jcpsp.2025.01.76\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The study assessed the effectiveness and safety of nerve block combined with low-dose general anaesthesia in elderly hip arthroplasty patients, conducted by a meta-analysis of RCTs. Six trials involving 403 patients were identified from databases such as Cochrane, MEDLINE, and PubMed. The results demonstrated a statistically significant difference in pain scores at postoperative 12hours (95% CI, -2.39 to -0.35, p = 0.008) and 24hours (95% CI, -1.86 to -0.50, p = 0.0007). Nerve block in combination with general anaesthesia holds a significant advantage over conventional general anaesthesia regarding perioperative opioid consumption (95% CI, -38.32 to -7.48, p = 0.004). This combined approach was superior in reducing the incidence of complications (95% CI, 0.11 to 0.55, p = 0.0007). However, between the two groups, there was no statistically significant difference in the 48hour pain score (95% CI, -2.58 to 0.62, p = 0.23). Essentially, this approach effectively reduces early post-surgical pain and it minimises anaesthetic use, whilst simultaneously lowering the risk of complications. Key Words: Nerve block, Elderly patients, Hip arthroplasty, Pain, Postoperative complication.</p>\",\"PeriodicalId\":94116,\"journal\":{\"name\":\"Journal of the College of Physicians and Surgeons--Pakistan : JCPSP\",\"volume\":\"35 1\",\"pages\":\"76-82\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the College of Physicians and Surgeons--Pakistan : JCPSP\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29271/jcpsp.2025.01.76\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the College of Physicians and Surgeons--Pakistan : JCPSP","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29271/jcpsp.2025.01.76","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
该研究通过随机对照试验的荟萃分析,评估了神经阻滞联合低剂量全身麻醉在老年髋关节置换术患者中的有效性和安全性。从Cochrane、MEDLINE和PubMed等数据库中确定了涉及403例患者的6项试验。结果显示,术后12小时(95% CI, -2.39 ~ -0.35, p = 0.008)和24小时(95% CI, -1.86 ~ -0.50, p = 0.0007)疼痛评分差异有统计学意义。在围手术期阿片类药物消耗方面,神经阻滞联合全身麻醉比常规全身麻醉具有显著优势(95% CI, -38.32至-7.48,p = 0.004)。该联合入路在降低并发症发生率方面具有优势(95% CI, 0.11 ~ 0.55, p = 0.0007)。但两组患者48小时疼痛评分差异无统计学意义(95% CI, -2.58 ~ 0.62, p = 0.23)。从本质上讲,这种方法有效地减少了早期术后疼痛,并最大限度地减少了麻醉剂的使用,同时降低了并发症的风险。关键词:神经阻滞,老年患者,髋关节置换术,疼痛,术后并发症。
Peripheral Nerve Block Combined with Low-Dose General Anaesthesia in Elderly Patients Receiving Hip Arthroplasty.
The study assessed the effectiveness and safety of nerve block combined with low-dose general anaesthesia in elderly hip arthroplasty patients, conducted by a meta-analysis of RCTs. Six trials involving 403 patients were identified from databases such as Cochrane, MEDLINE, and PubMed. The results demonstrated a statistically significant difference in pain scores at postoperative 12hours (95% CI, -2.39 to -0.35, p = 0.008) and 24hours (95% CI, -1.86 to -0.50, p = 0.0007). Nerve block in combination with general anaesthesia holds a significant advantage over conventional general anaesthesia regarding perioperative opioid consumption (95% CI, -38.32 to -7.48, p = 0.004). This combined approach was superior in reducing the incidence of complications (95% CI, 0.11 to 0.55, p = 0.0007). However, between the two groups, there was no statistically significant difference in the 48hour pain score (95% CI, -2.58 to 0.62, p = 0.23). Essentially, this approach effectively reduces early post-surgical pain and it minimises anaesthetic use, whilst simultaneously lowering the risk of complications. Key Words: Nerve block, Elderly patients, Hip arthroplasty, Pain, Postoperative complication.