探索含硼化合物在生物系统中的作用：潜在的应用和关键挑战。

IF 3.6 3区医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Trace Elements in Medicine and Biology Pub Date : 2025-02-01 DOI:10.1016/j.jtemb.2025.127594

Haseeb Khaliq

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引用次数: 0

摘要

背景：硼是一种天然丰富的微量元素，在多种生物过程中起着至关重要的作用，影响着骨骼健康、免疫反应和细胞代谢等重要生理功能。它的应用范围包括解剖学、药理学、生殖学、医学和农业等多个科学领域。目的：本文综述了硼化合物在生物系统中的多种功能，并强调了它们的治疗潜力、与毒性相关的挑战以及它们生物相互作用的机制。方法：本文综述了硼作用的相关文献，重点介绍了硼对健康的影响及其在多个领域的治疗应用。结果：硼通过影响多种途径显示出广泛的治疗潜力。然而，过量食用会导致中毒并对健康产生负面影响。目前的研究只对硼的生物学效应机制有部分的阐明，还需要进一步的研究。结论：了解硼在生物系统中的相互作用对优化其在医疗保健中的应用和确保其安全性至关重要。未来的研究将提高我们对硼的生物学效应的认识，促进创新的治疗应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Exploring the role of boron-containing compounds in biological systems: Potential applications and key challenges

Background

Boron, a naturally abundant trace element, plays a crucial role in various biological processes and influences important physiological functions such as bone health, immune response, and cellular metabolism. Its applications span diverse scientific fields including anatomy, pharmacology, reproduction, medicine, and agriculture.

Objectives

This review examines the diverse functions of boron-compounds in biological systems and highlights their therapeutic potential, challenges associated with toxicity, and mechanisms underlying their biological interactions.

Methods

In this paper, the literature on boron action was reviewed, paying special attention to studies that examined the effects of boron on health and its therapeutic applications in multiple areas.

Results

Boron exhibits broad therapeutic potential by affecting several pathways. However, excessive consumption can cause toxicity and negatively impact health. Current research only partially elucidates the mechanisms of boron's biological effects, so further studies are needed.

Conclusion

Understanding boron's interactions in biological systems is critical to optimizing its application in healthcare and ensuring safety. Future research will improve our knowledge of boron's biological effects and promote innovative therapeutic applications.

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来源期刊

Journal of Trace Elements in Medicine and Biology 医学-内分泌学与代谢

CiteScore

6.60

自引率

2.90%

发文量

202

审稿时长

85 days

期刊介绍： The journal provides the reader with a thorough description of theoretical and applied aspects of trace elements in medicine and biology and is devoted to the advancement of scientific knowledge about trace elements and trace element species. Trace elements play essential roles in the maintenance of physiological processes. During the last decades there has been a great deal of scientific investigation about the function and binding of trace elements. The Journal of Trace Elements in Medicine and Biology focuses on the description and dissemination of scientific results concerning the role of trace elements with respect to their mode of action in health and disease and nutritional importance. Progress in the knowledge of the biological role of trace elements depends, however, on advances in trace elements chemistry. Thus the Journal of Trace Elements in Medicine and Biology will include only those papers that base their results on proven analytical methods. Also, we only publish those articles in which the quality assurance regarding the execution of experiments and achievement of results is guaranteed.