Hongyu Xing , Hao Luo , Lei Lai , Hongyu Zhao , Runqi Xue , Qingguo Lai
{"title":"颞下颌关节椎间盘复位手术中氧化锆锚钉的SLA-3D打印及生物活性增强。","authors":"Hongyu Xing , Hao Luo , Lei Lai , Hongyu Zhao , Runqi Xue , Qingguo Lai","doi":"10.1016/j.jmbbm.2025.106897","DOIUrl":null,"url":null,"abstract":"<div><div>A method is proposed for 3D printing and enhancing the surface bioactivity of zirconia ceramic anchor screws, specifically tailored for temporomandibular joint disc reduction surgery. Initially, the challenge posed by the brittleness and processing difficulties of fine ceramic anchor screws was addressed through the application of SLA-3D printing technology. This allowed for an exploration of the forming accuracy and biomechanical properties of the printed anchor screws. According to research findings, the dimensional deviation in the thread processing of 3D printed zirconia screws is approximately 100 μm. When the threaded segment measures 7.0 mm in length, the 3D printed zirconia anchor screw, with a diameter of 2.7 mm, demonstrates comparable maximum axial tensile forces 102.91 N to a titanium screw of 2.0 mm diameter. The maximum vertical tensile force of the zirconia anchor screws exceeds the breaking force of the anchor suture by 21.03 N, fulfilling the requirements for clinical application. Additionally, the application of a ZrO<sub>2</sub>-PDA-La<sup>3+</sup> composite biological coating enhances the surface bioactivity of the 3D printed zirconia anchor screws. PDA ensures reliable adhesion of the biological coating during the implantation process, while La<sup>3+</sup> significantly boosts the osteogenic capacity of the zirconia ceramic surface, thereby contributing to the long-term stability of the implant. Ultimately, zirconia anchor screws satisfying basic clinical requirements in terms of mechanical properties and biological activity were successfully developed, offering a novel treatment option for ADDwoR patients, particularly those with metal allergies.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"163 ","pages":"Article 106897"},"PeriodicalIF":3.3000,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SLA-3D printing and bioactivity enhancement of zirconia anchor screws for temporomandibular joint disc reduction surgery\",\"authors\":\"Hongyu Xing , Hao Luo , Lei Lai , Hongyu Zhao , Runqi Xue , Qingguo Lai\",\"doi\":\"10.1016/j.jmbbm.2025.106897\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A method is proposed for 3D printing and enhancing the surface bioactivity of zirconia ceramic anchor screws, specifically tailored for temporomandibular joint disc reduction surgery. Initially, the challenge posed by the brittleness and processing difficulties of fine ceramic anchor screws was addressed through the application of SLA-3D printing technology. This allowed for an exploration of the forming accuracy and biomechanical properties of the printed anchor screws. According to research findings, the dimensional deviation in the thread processing of 3D printed zirconia screws is approximately 100 μm. When the threaded segment measures 7.0 mm in length, the 3D printed zirconia anchor screw, with a diameter of 2.7 mm, demonstrates comparable maximum axial tensile forces 102.91 N to a titanium screw of 2.0 mm diameter. The maximum vertical tensile force of the zirconia anchor screws exceeds the breaking force of the anchor suture by 21.03 N, fulfilling the requirements for clinical application. Additionally, the application of a ZrO<sub>2</sub>-PDA-La<sup>3+</sup> composite biological coating enhances the surface bioactivity of the 3D printed zirconia anchor screws. PDA ensures reliable adhesion of the biological coating during the implantation process, while La<sup>3+</sup> significantly boosts the osteogenic capacity of the zirconia ceramic surface, thereby contributing to the long-term stability of the implant. Ultimately, zirconia anchor screws satisfying basic clinical requirements in terms of mechanical properties and biological activity were successfully developed, offering a novel treatment option for ADDwoR patients, particularly those with metal allergies.</div></div>\",\"PeriodicalId\":380,\"journal\":{\"name\":\"Journal of the Mechanical Behavior of Biomedical Materials\",\"volume\":\"163 \",\"pages\":\"Article 106897\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-01-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Mechanical Behavior of Biomedical Materials\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S175161612500013X\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Mechanical Behavior of Biomedical Materials","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S175161612500013X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
SLA-3D printing and bioactivity enhancement of zirconia anchor screws for temporomandibular joint disc reduction surgery
A method is proposed for 3D printing and enhancing the surface bioactivity of zirconia ceramic anchor screws, specifically tailored for temporomandibular joint disc reduction surgery. Initially, the challenge posed by the brittleness and processing difficulties of fine ceramic anchor screws was addressed through the application of SLA-3D printing technology. This allowed for an exploration of the forming accuracy and biomechanical properties of the printed anchor screws. According to research findings, the dimensional deviation in the thread processing of 3D printed zirconia screws is approximately 100 μm. When the threaded segment measures 7.0 mm in length, the 3D printed zirconia anchor screw, with a diameter of 2.7 mm, demonstrates comparable maximum axial tensile forces 102.91 N to a titanium screw of 2.0 mm diameter. The maximum vertical tensile force of the zirconia anchor screws exceeds the breaking force of the anchor suture by 21.03 N, fulfilling the requirements for clinical application. Additionally, the application of a ZrO2-PDA-La3+ composite biological coating enhances the surface bioactivity of the 3D printed zirconia anchor screws. PDA ensures reliable adhesion of the biological coating during the implantation process, while La3+ significantly boosts the osteogenic capacity of the zirconia ceramic surface, thereby contributing to the long-term stability of the implant. Ultimately, zirconia anchor screws satisfying basic clinical requirements in terms of mechanical properties and biological activity were successfully developed, offering a novel treatment option for ADDwoR patients, particularly those with metal allergies.
期刊介绍:
The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials.
The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.