植物源性外泌体样纳米颗粒在组织修复和再生中的应用。

IF 6.1 3区医学 Q1 MATERIALS SCIENCE, BIOMATERIALS

Journal of Materials Chemistry B Pub Date : 2024-12-18 DOI:10.1039/D4TB02394C

Canyu Gao, Yang Chen, Xingyue Wen, Ruiying Han, Yuxiang Qin, Sijie Li, Rong Tang, Weikai Zhou, Junyu Zhao, Jianxun Sun, Zhengyong Li, Zhen Tan, Deli Wang and Changchun Zhou

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引用次数: 0

摘要

本文综述了植物源性外泌体样纳米颗粒（ELNs），并强调了其在再生医学中的潜力。讨论了各种提取技术，包括超离心和超滤，以及它们对ELN纯度和收率的影响。表征方法，如显微镜和颗粒分析被发现在定义ELN性质中起着至关重要的作用。本文将重点探讨eln在组织修复、免疫调节和抗氧化活性方面的治疗潜力。需要进一步研究和优化神经网络提取方法，以实现临床应用潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Plant-derived exosome-like nanoparticles in tissue repair and regeneration

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Plant-derived exosome-like nanoparticles in tissue repair and regeneration

This article reviews plant-derived exosome-like nanoparticles (ELNs), and highlights their potential in regenerative medicine. Various extraction techniques, including ultracentrifugation and ultrafiltration, and their impact on ELN purity and yield were discussed. Characterization methods such as microscopy and particle analysis are found to play crucial roles in defining ELN properties. This review is focused on exploring the therapeutic potential of ELNs in tissue repair, immune regulation, and antioxidant activities. Further research and optimization methods for extraction of ELNs to realize clinical potential applications are necessary.

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来源期刊

Journal of Materials Chemistry B MATERIALS SCIENCE, BIOMATERIALS-

CiteScore

11.50

自引率

4.30%

发文量

866

期刊介绍： Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C.Journal of Materials Chemistry B is a Transformative Journal and Plan S compliant. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive： Antifouling coatings Biocompatible materials Bioelectronics Bioimaging Biomimetics Biomineralisation Bionics Biosensors Diagnostics Drug delivery Gene delivery Immunobiology Nanomedicine Regenerative medicine & Tissue engineering Scaffolds Soft robotics Stem cells Therapeutic devices