在光学相干层析成像中实现高精度衰减系数测量。

IF 2 3区物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS

Journal of Biophotonics Pub Date : 2025-01-16 DOI:10.1002/jbio.202400395

Linda B. Neubrand, Xavier Attendu, Ton G. van Leeuwen

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引用次数: 0

摘要

在这项研究中，我们的目标是利用1310 nm光学相干层析成像（OCT）系统验证用于确定衰减系数的解析性Cramer-Rao下界（CRLB）方程。我们的实验结果成功地证实了方程的有效性，在脂质内样品的标准偏差低于0.01 mm-1的情况下实现了前所未有的精度。此外，我们还介绍了一种用于实现高精度OCT衰减测量的系统框架。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Achieving High-Precision Attenuation Coefficient Measurement in Optical Coherence Tomography

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Achieving High-Precision Attenuation Coefficient Measurement in Optical Coherence Tomography

In this study, we aim to validate the analytical Cramer-Rao lower bound (CRLB) equation for determining attenuation coefficients using a 1310 nm Optical Coherence Tomography (OCT) system. Our experimental results successfully confirm the validity of the equation, achieving unprecedented precision with a standard deviation below 0.01 mm⁻¹ for intralipid samples. Furthermore, we introduce a systematic framework for attaining high precision in OCT attenuation measurements.

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来源期刊

Journal of Biophotonics 生物-生化研究方法

CiteScore

5.70

自引率

7.10%

发文量

248

审稿时长

1 months

期刊介绍： The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.