Ingrid Preteseille DVM, MSc, Steven E. Epstein DVM, DACVECC, Kate Hopper BVSc, PhD, DACVECC
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Determination of reference intervals of venous blood gas and acid–base parameters in clinically healthy awake cats
Background
Venous blood gas and acid–base analysis is often performed in cats and requires appropriate reference intervals (RIs) for interpretation. The currently available RIs were created from small numbers of cats, while current guidelines suggest that a minimum number of 40 samples is required for the creation of an accurate/appropriate RI.
Key Findings
In 41 healthy awake cats, pH, PvCO2, PvO2, sodium, potassium, ionized calcium, chloride, glucose, and plasma lactate concentrations were measured, while bicarbonate, standardized base excess, and anion gap were calculated. These data were used to calculate RIs, using a statistical approach that conforms to the American Society for Veterinary Clinical Pathology guidelines.
Significance
RIs for venous blood gas and traditional acid–base analysis from a relatively large population of healthy cats are now available for clinical use and standardized for future research studies.
期刊介绍:
The Journal of Veterinary Emergency and Critical Care’s primary aim is to advance the international clinical standard of care for emergency/critical care patients of all species. The journal’s content is relevant to specialist and non-specialist veterinarians practicing emergency/critical care medicine. The journal achieves it aims by publishing descriptions of unique presentation or management; retrospective and prospective evaluations of prognosis, novel diagnosis, or therapy; translational basic science studies with clinical relevance; in depth reviews of pertinent topics; topical news and letters; and regular themed issues.
The journal is the official publication of the Veterinary Emergency and Critical Care Society, the American College of Veterinary Emergency and Critical Care, the European Veterinary Emergency and Critical Care Society, and the European College of Veterinary Emergency and Critical Care. It is a bimonthly publication with international impact and adheres to currently accepted ethical standards.