导航一个复杂的舞蹈:在口腔上皮可塑性中rna结合蛋白和T细胞之间的相互作用。

Immunometabolism (Cobham (Surrey, England)) Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI:10.1097/IN9.0000000000000054
Anitha Vijayakumar, Sekar Vasudevan, Samu John, Michelle A Ozbun, Eric Bartee, Viswanathan Palanisamy
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引用次数: 0

摘要

口腔上皮是一个不断面临环境挑战的动态界面,它依靠复杂的分子途径来维持自身的稳态。这篇全面的综述深入研究了口腔上皮内T淋巴细胞(T细胞)和rna结合蛋白(rbp)之间微妙的相互作用,阐明了它们在协调免疫反应和影响组织可塑性中的作用。通过综合目前的知识,我们的目标是解开控制这种相互作用的分子复杂性,重点是对口腔健康和疾病的潜在治疗意义。了解由T细胞和rbp在口腔上皮微环境中形成的调节网络,有望为管理与上皮功能障碍相关的疾病提供创新策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Navigating a complex dance: the interplay between RNA-binding proteins and T cells in oral epithelial plasticity.

The oral epithelium, a dynamic interface constantly facing environmental challenges, relies on intricate molecular pathways to maintain its homeostasis. This comprehensive review delves into the nuanced interplay between T-lymphocytic cells (T cells) and RNA-binding proteins (RBPs) within the oral epithelium, elucidating their roles in orchestrating immune responses and influencing tissue plasticity. By synthesizing current knowledge, we aim to unravel the molecular intricacies that govern this interplay, with a focus on potential therapeutic implications for oral health and diseases. Understanding the regulatory networks shaped by T cells and RBPs in the oral epithelial microenvironment holds promise for innovative strategies in managing conditions associated with epithelial dysfunction.

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