[18-50岁男性原发性和复发性缺血性卒中的特点]。

Q3 Medicine

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova Pub Date : 2024-01-01 DOI:10.17116/jnevro202412412265

N A Pizov, M V Bakucheva, O P Rechkina

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引用次数: 0

摘要

目的：评价18-50岁男性动脉粥样硬化血栓、腔隙性和心脏栓塞亚型原发性和复发性卒中的特点。材料和方法：共有125名男性原发性和复发性卒中患者纳入研究。评估主要血管危险因素及生活方式相关危险因素。行神经学、神经影像学、超声及实验室检查。研究止血指标、脂质代谢指标和内皮功能指标。结果：125例中位年龄为43岁的男性缺血性卒中患者中，104例（83.2%）患者为原发性卒中，21例（16.8%）患者为复发性卒中。复发性卒中在心脏栓塞亚型患者中发生率更高（26.3%），在动脉粥样硬化血栓形成亚型（13.3%）和腔隙性亚型（17.4%）患者中发生率几乎相同。在整个组中，原发性和复发性卒中患者的年龄没有差异（分别为43.1±5.5岁和43.7±4.3岁）。通过对不同脑卒中亚型的原发性和复发性脑卒中患者进行对比分析，发现主要危险因素、脂质代谢指标、止血指标和内皮功能指标存在显著差异。结论：通过对18-50岁男性动脉粥样硬化血栓、腔隙性和心栓亚型的研究，揭示了原发性和复发性脑卒中的危险因素、止血系统指标、脂质代谢和内皮功能的特点。

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[Features of primary and recurrent ischemic stroke in men aged 18-50 years].

Objective: To evaluate the features of primary and recurrent stroke in men aged 18-50 years with atherothrombotic, lacunar, and cardioembolic subtypes.

Material and methods: A total of 125 men with primary and recurrent stroke were included in the study. The main vascular risk factors and lifestyle-related risk factors were assessed. Neurological, neuroimaging, ultrasound and laboratory examinations were performed. Hemostasis parameters, lipid metabolism and endothelial function parameters were studied.

Results: Among 125 men with ischemic stroke with a median age of 43 years, 104 (83.2%) patients had a primary stroke and 21 (16.8%) patients had a recurrent stroke. Recurrent stroke occurred more frequently in patients with the cardioembolic subtype (26.3%) and with almost equal frequency in patients with the atherothrombotic (13.3%) and lacunar (17.4%) subtypes. In the group as a whole, patients with primary and recurrent strokes did not differ in age (43.1±5.5 and 43.7±4.3 years, respectively). In a comparative analysis of patients with primary and recurrent stroke with different subtypes of stroke, significant differences in the main risk factors, indicators of lipid metabolism, hemostasis and endothelial function were obtained.

Conclusion: The study in men, aged 18-50 years, with atherothrombotic, lacunar and cardioembolic subtypes revealed the features of risk factors, indicators of hemostasis system, lipid metabolism and endothelial function in primary and recurrent stroke.

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来源期刊

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova 医学-精神病学

CiteScore

1.10

自引率

0.00%

发文量

287

审稿时长

3-6 weeks

期刊介绍： Одно из старейших медицинских изданий России, основанное в 1901 году. Создание журнала связано с именами выдающихся деятелей отечественной медицины, вошедших в историю мировой психиатрии и неврологии, – С.С. Корсакова и А.Я. Кожевникова. Широкий диапазон предлагаемых журналом материалов и разнообразие форм их представления привлекают внимание научных работников и врачей, опытных и начинающих медиков, причем не только неврологов и психиатров, но и специалистов смежных областей медицины.