{"title":"水助微波辐照降解玉米黄曲霉毒素B1及其动力学研究。","authors":"Yaolei Zhang, Lingling Zhang, Xiaoxia Zhang, Cheng Zhao, Mengmeng Li, Erqi Guan, Yangyong Lv, Ke Bian","doi":"10.1016/j.toxicon.2025.108239","DOIUrl":null,"url":null,"abstract":"<p><p>Aflatoxin B<sub>1</sub> (AFB<sub>1</sub>) is a highly toxic, carcinogenic, teratogenic, and mutagenic mycotoxin commonly found in corn. In this work, water-assisted microwave irradiation (WMI<sup>1</sup>) was used to degrade AFB<sub>1</sub> in corn, during which the influencing factors and kinetics of AFB<sub>1</sub> degradation were also studied. The results showed that the degree of corn crushing, the heating rate of WMI, the temperature of WMI, the solid-liquid ratio, the initial content of AFB<sub>1</sub> and the microwave power were all important factors affecting the degradation of AFB<sub>1</sub>. With the increase of WMI temperature, AFB<sub>1</sub> content in corn, microwave power and the decrease of solid-liquid ratio, the degradation rate of AFB<sub>1</sub> in corn by WMI rose continuously. Its maximum degradation rate was more than 90.6%. Meanwhile, the degradation kinetics of AFB<sub>1</sub> in corn revealed that the degradation process of WMI followed a pseudo-first-order kinetic equation. It was demonstrated that water molecules not only acted as solvents for AFB<sub>1</sub> but also actively participated in its degradation process within corn samples during WMI treatment. Consequently, the results indicated that WMI was an effective method for degrading AFB<sub>1</sub> in corn.</p>","PeriodicalId":23289,"journal":{"name":"Toxicon","volume":"255 ","pages":"108239"},"PeriodicalIF":2.6000,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Degradation of aflatoxin B<sub>1</sub> in corn by water-assisted microwave irradiation and its kinetic.\",\"authors\":\"Yaolei Zhang, Lingling Zhang, Xiaoxia Zhang, Cheng Zhao, Mengmeng Li, Erqi Guan, Yangyong Lv, Ke Bian\",\"doi\":\"10.1016/j.toxicon.2025.108239\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Aflatoxin B<sub>1</sub> (AFB<sub>1</sub>) is a highly toxic, carcinogenic, teratogenic, and mutagenic mycotoxin commonly found in corn. In this work, water-assisted microwave irradiation (WMI<sup>1</sup>) was used to degrade AFB<sub>1</sub> in corn, during which the influencing factors and kinetics of AFB<sub>1</sub> degradation were also studied. The results showed that the degree of corn crushing, the heating rate of WMI, the temperature of WMI, the solid-liquid ratio, the initial content of AFB<sub>1</sub> and the microwave power were all important factors affecting the degradation of AFB<sub>1</sub>. With the increase of WMI temperature, AFB<sub>1</sub> content in corn, microwave power and the decrease of solid-liquid ratio, the degradation rate of AFB<sub>1</sub> in corn by WMI rose continuously. Its maximum degradation rate was more than 90.6%. Meanwhile, the degradation kinetics of AFB<sub>1</sub> in corn revealed that the degradation process of WMI followed a pseudo-first-order kinetic equation. It was demonstrated that water molecules not only acted as solvents for AFB<sub>1</sub> but also actively participated in its degradation process within corn samples during WMI treatment. Consequently, the results indicated that WMI was an effective method for degrading AFB<sub>1</sub> in corn.</p>\",\"PeriodicalId\":23289,\"journal\":{\"name\":\"Toxicon\",\"volume\":\"255 \",\"pages\":\"108239\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-01-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Toxicon\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.toxicon.2025.108239\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicon","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.toxicon.2025.108239","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Degradation of aflatoxin B1 in corn by water-assisted microwave irradiation and its kinetic.
Aflatoxin B1 (AFB1) is a highly toxic, carcinogenic, teratogenic, and mutagenic mycotoxin commonly found in corn. In this work, water-assisted microwave irradiation (WMI1) was used to degrade AFB1 in corn, during which the influencing factors and kinetics of AFB1 degradation were also studied. The results showed that the degree of corn crushing, the heating rate of WMI, the temperature of WMI, the solid-liquid ratio, the initial content of AFB1 and the microwave power were all important factors affecting the degradation of AFB1. With the increase of WMI temperature, AFB1 content in corn, microwave power and the decrease of solid-liquid ratio, the degradation rate of AFB1 in corn by WMI rose continuously. Its maximum degradation rate was more than 90.6%. Meanwhile, the degradation kinetics of AFB1 in corn revealed that the degradation process of WMI followed a pseudo-first-order kinetic equation. It was demonstrated that water molecules not only acted as solvents for AFB1 but also actively participated in its degradation process within corn samples during WMI treatment. Consequently, the results indicated that WMI was an effective method for degrading AFB1 in corn.
期刊介绍：
Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee.
Toxicon''s "aims and scope" are to publish:
-articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms
-papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins
-molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins
-clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained.
-material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems.
-articles on the translational application of toxins, for example as drugs and insecticides
-epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged.
-articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon.
-review articles on problems related to toxinology.
To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.
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