减肥手术患者的阻塞性睡眠呼吸暂停:一项基于人群的研究

IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY
Vanessa Martelli, Aristithes G Doumouras, Lawrence Mbuagbaw, Najib Ayas, Jean-Eric Tarride
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引用次数: 0

摘要

目的:阻塞性睡眠呼吸暂停(OSA)的高比例仍未确诊。本研究的主要目的是测量接受减肥手术的患者中诊断出的OSA的患病率,并确定OSA的预测因素,这些患者主要是女性和绝经前患者,在OSA文献中属于研究不足的人群。方法:这是一项基于人群的横断面研究,使用2010年至2016年安大略省肥胖登记处(OBR),与ICES数据库相关联,该数据库包括单一公共支付系统内所有就诊的卫生管理数据。采用多元逻辑回归测量OSA的预测因子。结果:在接受减肥手术的18,074例患者中,47%的患者被诊断为OSA(95%置信区间[CI]: 46至47),OSA是该人群中第二常见的合并症。在首次减肥咨询时,只有63%的OSA诊断被记录在OBR中。在相互作用的基础上,研究发现,除了男性的预测因素(年龄、体重指数和合并症负担)外,女性的OSA预测因素还包括社会不平等、糖尿病和慢性阻塞性肺病。结论:在首次减肥手术会诊的患者中,有相当大比例的患者未确诊OSA。OSA筛查和检测可能导致OSA的漏诊,特别是绝经前女性,她们代表了大多数接受减肥手术的人群。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Obstructive sleep apnea in bariatric surgery patients: a population-based study.

Purpose: A high proportion of obstructive sleep apnea (OSA) remains undiagnosed. The main objectives of this study were to measure the prevalence of diagnosed OSA and determine OSA predictors in patients who underwent bariatric surgery, who are predominantly female and pre-menopausal and represent an understudied population in OSA literature.

Methods: This was a cross-sectional population-based study using the Ontario Bariatric Registry (OBR) from 2010 to 2016, linked to ICES databases which include health administrative data on all encounters within a single public-payer system. Multiple logistic regression was used to measure OSA predictors.

Results: Out of a total of 18,074 patients who underwent bariatric surgery, OSA was diagnosed in 47% (95% confidence interval [CI]: 46 to 47), and OSA was the second most common comorbidity within this population. Only 63% of OSA diagnoses were recorded in the OBR at the time of initial bariatric consultation. Based on interaction, it was found that, in females, OSA predictors included social inequality, diabetes and chronic obstructive pulmonary disease, in addition to the predictors measured in males (age, body mass index and comorbidity burden).

Conclusion: A significant proportion of patients presenting for initial bariatric surgery consultation have undiagnosed OSA. OSA screening and testing may lead to underdiagnosis of OSA, especially in pre-menopausal females who represent the majority of the population undergoing bariatric surgery.

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来源期刊
Sleep and Breathing
Sleep and Breathing 医学-呼吸系统
CiteScore
5.20
自引率
4.00%
发文量
222
审稿时长
3-8 weeks
期刊介绍: The journal Sleep and Breathing aims to reflect the state of the art in the international science and practice of sleep medicine. The journal is based on the recognition that management of sleep disorders requires a multi-disciplinary approach and diverse perspectives. The initial focus of Sleep and Breathing is on timely and original studies that collect, intervene, or otherwise inform all clinicians and scientists in medicine, dentistry and oral surgery, otolaryngology, and epidemiology on the management of the upper airway during sleep. Furthermore, Sleep and Breathing endeavors to bring readers cutting edge information about all evolving aspects of common sleep disorders or disruptions, such as insomnia and shift work. The journal includes not only patient studies, but also studies that emphasize the principles of physiology and pathophysiology or illustrate potentially novel approaches to diagnosis and treatment. In addition, the journal features articles that describe patient-oriented and cost-benefit health outcomes research. Thus, with peer review by an international Editorial Board and prompt English-language publication, Sleep and Breathing provides rapid dissemination of clinical and clinically related scientific information. But it also does more: it is dedicated to making the most important developments in sleep disordered breathing easily accessible to clinicians who are treating sleep apnea by presenting well-chosen, well-written, and highly organized information that is useful for patient care.
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