用多普勒光学相干断层扫描比较镰状细胞病患者稳定状态和健康状态下的视网膜血流参数。

IF 0.9 4区医学 Q4 OPHTHALMOLOGY

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-01-01 DOI:10.3928/23258160-20241114-03

Hernan A Rios, Sofia Ahsanuddin, Oscar Otero-Marquez, Luis Duran Muncharaz, Kana Minamide, Jordan Bellis, Elizabeth Stidham, Toco Y P Chui, Masahiro Akiba, Jeffrey A Glassberg, Richard B Rosen

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引用次数: 0

摘要

背景与目的：镰状细胞病（SCD）是一种可能影响视网膜的血管性疾病。本研究旨在利用多普勒光学相干断层扫描（DOCT）评价SCD患者颞视网膜拱廊的平均速度（AV, mm/s）、血流（BF, μL/min）和血管直径（VD, μm）与健康眼的差异。患者和方法：在2021年至2023年间进行了一项横断面研究。DOCT扫描位于所有受试者的颞血管上、下拱廊。评估两组之间的差异。结果：正常眼39只，SCD眼36只。SCD眼颞上动脉的AV、BF和VD中位数分别是健康眼的1.4、2.5和1.3倍（P = 0.002, P = 5.0 × 10-3, P = 4.0 × 10-6）。在颞上静脉和颞下静脉中观察到类似的结果。结论：与健康眼相比，SCD眼的视网膜血管血流参数明显升高。[眼科外科激光成像视网膜2025；56:XX-XX]。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Comparison of Retinal Blood Flow Parameters in Sickle Cell Disease at Steady State and Healthy Subjects Using Doppler Optical Coherence Tomography.

Background and objective: Sickle cell disease (SCD) is a vascular disease that may affect the retina. This study aimed to evaluate differences in average velocity (AV, mm/s), blood flow (BF, μL/min) and vessel diameter (VD, μm) from the temporal retinal arcades in SCD compared to healthy eyes using Doppler optical coherence tomography (DOCT).

Patients and methods: A cross-sectional study was conducted between 2021 and 2023. The DOCT scan was located at the superior and inferior temporal vessel arcades of all subjects. Differences between the two groups were assessed.

Results: Thirty-nine healthy eyes and 36 SCD eyes were imaged. The median of AV, BF, and VD were 1.4, 2.5, and 1.3 times higher in SCD eyes compared to healthy eyes in the superotemporal arteries (P = 0.002, P = 5.0 × 10-3, P = 4.0 × 10-6, respectively). Similar findings were observed for superotemporal veins and inferotemporal veins.

Conclusion: Eyes with SCD eyes exhibited significantly elevated retinal vascular flow parameters compared to healthy eyes. [Ophthalmic Surg Lasers Imaging Retina 2025;56:XX-XX.].

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来源期刊

Ophthalmic surgery, lasers & imaging retina OPHTHALMOLOGY-SURGERY

CiteScore

1.80

自引率

0.00%

发文量

期刊介绍： OSLI Retina focuses exclusively on retinal diseases, surgery and pharmacotherapy. OSLI Retina will offer an expedited submission to publication effort of peer-reviewed clinical science and case report articles. The front of the journal offers practical clinical and practice management features and columns specific to retina specialists. In sum, readers will find important peer-reviewed retina articles and the latest findings in techniques and science, as well as informative business and practice management features in one journal.