鞘内巴氯芬治疗期间导管断裂导致痉挛加重:1例报告。

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL
Yasutaka Takagi, Hiroshi Yamada, Hidehumi Ebara, Hiroyuki Hayashi, Hiroyuki Inatani, Yuta Nakamura, Ryo Sugihara, Aki Nakanami, Kenji Kagechika, Tetsutaro Yahata, Satoru Demura
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引用次数: 0

摘要

背景:鞘内巴氯芬治疗可显著改善创伤性脊髓损伤、多发性硬化症、脑轻瘫或脊髓栓系综合征引起的严重痉挛患者的症状。鞘内导管相关的问题包括移位、撕裂、闭塞或断开。一些病例报告描述了导管碎片的处理。据我们所知,这是第一个关于新导管插入的详细报告。病例介绍:一名64岁日本男性脊髓性肌阵挛患者正在接受鞘内巴氯芬治疗;他的痉挛在鞘内巴氯芬治疗下得到了很好的控制,但在泵植入13年后恶化。影像学显示脊髓导管断裂,导管保留在椎管内。我们在不移除原有导管的情况下,通过不同的椎间隙插入新的导管。术后,痉挛在鞘内巴氯芬治疗下得到了很好的控制。结论:这是首次在不拔除旧鞘内导管的情况下,在不同椎间隙插入新导管进行鞘内巴氯芬治疗的详细报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Worsening spasticity due to catheter breakage during intrathecal baclofen therapy: a case report.

Background: Intrathecal baclofen therapy can substantially improve symptoms in patients with severe spasticity owing to traumatic spinal cord injury, multiple sclerosis, cerebral paresis, or tethered cord syndrome. Problems associated with intrathecal catheters include migration, laceration, occlusion, or disconnection. Several case reports have described the management of catheter fragments. To the best of our knowledge, this is the first detailed report of the insertion of a new catheter.

Case presentation: A 64-year-old Japanese man with spinal myoclonus was undergoing intrathecal baclofen therapy; his spasticity was well controlled with intrathecal baclofen therapy but worsened 13 years after pump implantation. Imaging revealed spinal catheter breakage, and the catheter was retained in the spinal canal. We inserted a new catheter through a different intervertebral space without removing the original catheter. Postoperatively, the spasticity remained well controlled with intrathecal baclofen therapy.

Conclusion: This is the first detailed report on the insertion of a new catheter for intrathecal baclofen therapy at a different intervertebral space from the catheter breakage, without removal of the old intrathecal catheter.

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来源期刊
Journal of Medical Case Reports
Journal of Medical Case Reports Medicine-Medicine (all)
CiteScore
1.50
自引率
0.00%
发文量
436
期刊介绍: JMCR is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. Reports should show one of the following: 1. Unreported or unusual side effects or adverse interactions involving medications 2. Unexpected or unusual presentations of a disease 3. New associations or variations in disease processes 4. Presentations, diagnoses and/or management of new and emerging diseases 5. An unexpected association between diseases or symptoms 6. An unexpected event in the course of observing or treating a patient 7. Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
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