妊娠期暴露于寨卡病毒的学龄前儿童的运动功能障碍和出生时的正常头畸形：发育协调障碍和轻度神经功能障碍。

IF 2.2 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Early human development Pub Date : 2025-02-01 DOI:10.1016/j.earlhumdev.2025.106198

Isabella Cristina Mendes de Sá e Silva , Carla Andrade Cardoso Tanuri Caldas , Marisa Marcia Mussi-Pinhata , Silvia Fabiana Biason de Moura Negrini , Carolina Portugal , Ana Paula Andrade Hamad , NATZIG cohort study members

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引用次数: 0

摘要

对61名产前暴露于寨卡病毒的正常头畸形婴儿在5至7岁时发生的运动功能障碍进行了评估。采用传统神经系统检查、Touwen神经系统检查、儿童运动评估量表-第二版（MABC-2）和发育协调障碍问卷（DCDQ）对发育协调障碍（DCD）和轻度神经功能障碍（MND）进行识别。运动功能障碍发生率高，47例（81.0%）为MND， 15例（24.5%）为可能的DCD。这两种情况之间也可能存在某种联系。

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Motor dysfunction in preschool children exposed to zika virus during pregnancy and normocephalic at birth: Developmental Coordination Disorder and Minimal Neurological Dysfunction

The occurrence of motor dysfunctions was assessed at the age of 5 to 7 years in 61 normocephalic infants with prenatal Zika virus exposure. Traditional neurological examination, Touwen neurological examination, Movement Assessment Battery for Children-Second Edition (MABC-2) and the Developmental Coordination Disorder Questionnaire (DCDQ) were used to identify Developmental Coordination Disorder (DCD) and Minimal Neurological Dysfunction (MND). A high frequency of motor dysfunctions was found, 47 (81.0 %) of MND and 15 (24.5 %) of probable DCD. It is also possible to suggest some association between both conditions.

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来源期刊

Early human development 医学-妇产科学

CiteScore

4.40

自引率

4.00%

发文量

100

审稿时长

46 days

期刊介绍： Established as an authoritative, highly cited voice on early human development, Early Human Development provides a unique opportunity for researchers and clinicians to bridge the communication gap between disciplines. Creating a forum for the productive exchange of ideas concerning early human growth and development, the journal publishes original research and clinical papers with particular emphasis on the continuum between fetal life and the perinatal period; aspects of postnatal growth influenced by early events; and the safeguarding of the quality of human survival. The first comprehensive and interdisciplinary journal in this area of growing importance, Early Human Development offers pertinent contributions to the following subject areas: Fetology; perinatology; pediatrics; growth and development; obstetrics; reproduction and fertility; epidemiology; behavioural sciences; nutrition and metabolism; teratology; neurology; brain biology; developmental psychology and screening.