{"title":"霍乱弧菌菌血症:一个不寻常的表现的病例报告。","authors":"Vinitha Alex , Mahavishnu Moodley","doi":"10.1016/j.diagmicrobio.2025.116685","DOIUrl":null,"url":null,"abstract":"<div><div>Infections by non-O1/non-O139 serogroups of <em>Vibrio cholerae</em> (NOVC) are increasing worldwide. Infected patients usually display self-limiting diarrhoea or external ear and wound infections. We present a rare case of bacteraemia secondary to NOVC infection. A 39-year-old male presented with acute onset of dyspnoea, chest pain, vomiting, diarrhoea and chronic bipedal oedema. He was hypoxic, acidotic, tachypnoeic, displayed tachycardia and an altered level of consciousness. The patient was assessed to be in congestive cardiac failure with acute gastroenteritis and hypoglycaemia, and was started on empiric co–amoxiclav. The blood culture flagged positive with <em>Vibrio cholerae</em> which was toxin negative and typed as NOVC. Unfortunately, the patient deteriorated in the emergency department and demised despite resuscitation efforts. This case demonstrates the possible severity of NOVC bacteraemia and its associated mortality, highlights the need for identification of potential risk factors and emphasizes the importance of sending appropriately collected samples for laboratory testing.</div></div>","PeriodicalId":11329,"journal":{"name":"Diagnostic microbiology and infectious disease","volume":"111 3","pages":"Article 116685"},"PeriodicalIF":2.1000,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Vibrio cholerae bacteraemia: A case report on an unusual presentation\",\"authors\":\"Vinitha Alex , Mahavishnu Moodley\",\"doi\":\"10.1016/j.diagmicrobio.2025.116685\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Infections by non-O1/non-O139 serogroups of <em>Vibrio cholerae</em> (NOVC) are increasing worldwide. Infected patients usually display self-limiting diarrhoea or external ear and wound infections. We present a rare case of bacteraemia secondary to NOVC infection. A 39-year-old male presented with acute onset of dyspnoea, chest pain, vomiting, diarrhoea and chronic bipedal oedema. He was hypoxic, acidotic, tachypnoeic, displayed tachycardia and an altered level of consciousness. The patient was assessed to be in congestive cardiac failure with acute gastroenteritis and hypoglycaemia, and was started on empiric co–amoxiclav. The blood culture flagged positive with <em>Vibrio cholerae</em> which was toxin negative and typed as NOVC. Unfortunately, the patient deteriorated in the emergency department and demised despite resuscitation efforts. This case demonstrates the possible severity of NOVC bacteraemia and its associated mortality, highlights the need for identification of potential risk factors and emphasizes the importance of sending appropriately collected samples for laboratory testing.</div></div>\",\"PeriodicalId\":11329,\"journal\":{\"name\":\"Diagnostic microbiology and infectious disease\",\"volume\":\"111 3\",\"pages\":\"Article 116685\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-01-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic microbiology and infectious disease\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0732889325000082\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic microbiology and infectious disease","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0732889325000082","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Vibrio cholerae bacteraemia: A case report on an unusual presentation
Infections by non-O1/non-O139 serogroups of Vibrio cholerae (NOVC) are increasing worldwide. Infected patients usually display self-limiting diarrhoea or external ear and wound infections. We present a rare case of bacteraemia secondary to NOVC infection. A 39-year-old male presented with acute onset of dyspnoea, chest pain, vomiting, diarrhoea and chronic bipedal oedema. He was hypoxic, acidotic, tachypnoeic, displayed tachycardia and an altered level of consciousness. The patient was assessed to be in congestive cardiac failure with acute gastroenteritis and hypoglycaemia, and was started on empiric co–amoxiclav. The blood culture flagged positive with Vibrio cholerae which was toxin negative and typed as NOVC. Unfortunately, the patient deteriorated in the emergency department and demised despite resuscitation efforts. This case demonstrates the possible severity of NOVC bacteraemia and its associated mortality, highlights the need for identification of potential risk factors and emphasizes the importance of sending appropriately collected samples for laboratory testing.
期刊介绍:
Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.