Maria Söderlund, Carl Almqvist, Olle Sjöström, Anna M Dahlin, Sara Sjöström, Barbro Numan Hellquist, Beatrice Melin, Maria Sandström
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The RISK North database, which links data from the National Cancer Quality Register with citizen demographic data from the Longitudinal Integration Database for Health Insurance and Labor Market Studies (LISA), the Total Population Registry (TPR), and the Geography Database (GD), was utilized to assess survival in patients with glioma in relation to education level, cohabitation status, travel time to regional hospitals, and region of residence.</p><p><strong>Results: </strong>In the multivariable analysis, longer survival was observed among WHO grade III-IV glioma patients with higher education level (middle school (ref) HR: 1, high school HR: 0.81 CI [0.67-0.98], p = 0.033; university/college HR: 0.81 CI [0.66-1.00], p = 0.048). 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引用次数: 0
摘要
目的：虽然社会人口因素，如社会经济地位（SES）、到医疗机构的旅行时间、同居状况和居住地区被观察到影响几种类型癌症的发病率和生存率，但尚不清楚是否在胶质瘤患者中观察到类似的影响。本研究探讨这些因素是否影响胶质瘤患者的生存。方法：在这项回顾性研究中，使用瑞典国家脑肿瘤质量登记处的数据，对2009年至2013年间存储的1276例WHO I-IV级胶质瘤患者进行了识别。RISK North数据库将来自国家癌症质量登记的数据与来自健康保险和劳动力市场研究纵向整合数据库（LISA）、总人口登记（TPR）和地理数据库（GD）的公民人口统计数据联系起来，用于评估胶质瘤患者的生存与教育水平、同居状况、前往地区医院的时间和居住地区的关系。结果：在多变量分析中，受教育程度较高的WHO III-IV级胶质瘤患者的生存期较长(中学（ref） HR: 1，高中HR: 0.81 CI [0.67-0.98], p = 0.033；大学/学院HR: 0.81 CI [0.66-1.00], p = 0.048)。在多变量生存分析中，生存与旅行时间、同居状态或居住地区无关。结论：在多变量生存分析中，低教育水平与WHO III级和IV级胶质瘤患者的生存降低有关，但与旅行时间、同居状态或居住地区无关。
The impact of socioeconomic status on glioma survival: a retrospective analysis.
Purpose: Although sociodemographic factors such as socioeconomic status (SES), travel time to health care, cohabitation status, and region of residence are observed to influence incidence and survival for several types of cancers, it is unclear whether similar effects have been observed in patients with glioma. This study investigates whether these factors affect survival for glioma patients.
Methods: In this retrospective study, the Swedish National Quality Registry for Brain Tumors was used to identify 1,276 patients with glioma WHO grade I-IV for whom data were deposited between 2009 and 2013. The RISK North database, which links data from the National Cancer Quality Register with citizen demographic data from the Longitudinal Integration Database for Health Insurance and Labor Market Studies (LISA), the Total Population Registry (TPR), and the Geography Database (GD), was utilized to assess survival in patients with glioma in relation to education level, cohabitation status, travel time to regional hospitals, and region of residence.
Results: In the multivariable analysis, longer survival was observed among WHO grade III-IV glioma patients with higher education level (middle school (ref) HR: 1, high school HR: 0.81 CI [0.67-0.98], p = 0.033; university/college HR: 0.81 CI [0.66-1.00], p = 0.048). Survival was not associated with travel time, cohabitation status, or region of residence in the multivariable survival analysis.
Conclusion: Low education level was associated with reduced survival for patients with glioma WHO grade III and IV in multivariable survival analyses, but no differences in survival were found in relation to travel time, cohabitation status, or region of residence.
期刊介绍：
Cancer Causes & Control is an international refereed journal that both reports and stimulates new avenues of investigation into the causes, control, and subsequent prevention of cancer. By drawing together related information published currently in a diverse range of biological and medical journals, it has a multidisciplinary and multinational approach.
The scope of the journal includes: variation in cancer distribution within and between populations; factors associated with cancer risk; preventive and therapeutic interventions on a population scale; economic, demographic, and health-policy implications of cancer; and related methodological issues.
The emphasis is on speed of publication. The journal will normally publish within 30 to 60 days of acceptance of manuscripts.
Cancer Causes & Control publishes Original Articles, Reviews, Commentaries, Opinions, Short Communications and Letters to the Editor which will have direct relevance to researchers and practitioners working in epidemiology, medical statistics, cancer biology, health education, medical economics and related fields. The journal also contains significant information for government agencies concerned with cancer research, control and policy.
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