{"title":"超声检查母体维生素D使用对胎儿锁骨发育的影响。","authors":"Fatma Ozdemir, Banu Acmaz, Fatma Latifoglu, Sabahattin Muhtaroglu, Nefise Tanrıdan Okcu, Gokhan Acmaz, Iptisam Ipek Muderris","doi":"10.1186/s12880-025-01558-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate the effect of maternal vitamin D use during intrauterine life on fetal bone development using ultrasonographic image processing techniques.</p><p><strong>Materials and methods: </strong>We evaluated 52 pregnant women receiving vitamin D supplementation and 50 who refused vitamin D supplementation. Ultrasonographic imaging was performed on the fetal clavicle at 37-40 weeks of gestation. The fetal clavicle images were compared with adult male clavicle images. The texture features obtained from these images were used for analysis.</p><p><strong>Results: </strong>No difference was observed in bone formation and destruction markers between the two groups. However, the texture analysis of ultrasonographic images revealed similarities in the characteristics of fetal clavicles in pregnant women receiving vitamin D supplementation and those of adult male clavicles.</p><p><strong>Conclusions: </strong>Vitamin D supplementation in pregnancy has significant positive effects on fetal bone maturation besides contributing to maternal bone health. Texture feature analyses using ultrasonographic images successfully demonstrated fetal bone maturation.</p>","PeriodicalId":9020,"journal":{"name":"BMC Medical Imaging","volume":"25 1","pages":"20"},"PeriodicalIF":2.9000,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740525/pdf/","citationCount":"0","resultStr":"{\"title\":\"Ultrasonographic examination of the maturational effect of maternal vitamin D use on fetal clavicle bone development.\",\"authors\":\"Fatma Ozdemir, Banu Acmaz, Fatma Latifoglu, Sabahattin Muhtaroglu, Nefise Tanrıdan Okcu, Gokhan Acmaz, Iptisam Ipek Muderris\",\"doi\":\"10.1186/s12880-025-01558-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>This study aimed to evaluate the effect of maternal vitamin D use during intrauterine life on fetal bone development using ultrasonographic image processing techniques.</p><p><strong>Materials and methods: </strong>We evaluated 52 pregnant women receiving vitamin D supplementation and 50 who refused vitamin D supplementation. Ultrasonographic imaging was performed on the fetal clavicle at 37-40 weeks of gestation. The fetal clavicle images were compared with adult male clavicle images. The texture features obtained from these images were used for analysis.</p><p><strong>Results: </strong>No difference was observed in bone formation and destruction markers between the two groups. However, the texture analysis of ultrasonographic images revealed similarities in the characteristics of fetal clavicles in pregnant women receiving vitamin D supplementation and those of adult male clavicles.</p><p><strong>Conclusions: </strong>Vitamin D supplementation in pregnancy has significant positive effects on fetal bone maturation besides contributing to maternal bone health. Texture feature analyses using ultrasonographic images successfully demonstrated fetal bone maturation.</p>\",\"PeriodicalId\":9020,\"journal\":{\"name\":\"BMC Medical Imaging\",\"volume\":\"25 1\",\"pages\":\"20\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-01-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740525/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Medical Imaging\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12880-025-01558-8\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Medical Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12880-025-01558-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Ultrasonographic examination of the maturational effect of maternal vitamin D use on fetal clavicle bone development.
Aim: This study aimed to evaluate the effect of maternal vitamin D use during intrauterine life on fetal bone development using ultrasonographic image processing techniques.
Materials and methods: We evaluated 52 pregnant women receiving vitamin D supplementation and 50 who refused vitamin D supplementation. Ultrasonographic imaging was performed on the fetal clavicle at 37-40 weeks of gestation. The fetal clavicle images were compared with adult male clavicle images. The texture features obtained from these images were used for analysis.
Results: No difference was observed in bone formation and destruction markers between the two groups. However, the texture analysis of ultrasonographic images revealed similarities in the characteristics of fetal clavicles in pregnant women receiving vitamin D supplementation and those of adult male clavicles.
Conclusions: Vitamin D supplementation in pregnancy has significant positive effects on fetal bone maturation besides contributing to maternal bone health. Texture feature analyses using ultrasonographic images successfully demonstrated fetal bone maturation.
期刊介绍：
BMC Medical Imaging is an open access journal publishing original peer-reviewed research articles in the development, evaluation, and use of imaging techniques and image processing tools to diagnose and manage disease.
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