摘要：12/15-脂氧合酶对β分泌酶-1的转录调控导致淀粉样蛋白生成增强和认知障碍。

IF 8.1 1区医学 Q1 CLINICAL NEUROLOGY

Annals of Neurology Pub Date : 2025-01-20 DOI:10.1002/ana.27184

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引用次数: 0

摘要

撤稿：J. Chu， J. m .。卓和D. Praticò，“12/15-脂氧合酶对β分泌酶-1的转录调控导致淀粉样蛋白形成和认知障碍，”神经病学年鉴71，no。1 (2012): 57-67, https://doi.org/10.1002/ana.22625。上述文章于2011年9月12日在线发表在Wiley在线图书馆（wileyonlinelibrary.com）上，经作者j - m。卓和D. Praticò；杂志主编肯尼斯·l·泰勒；美国神经学协会和Wiley期刊有限责任公司。由于图2A和4A所示的肌动蛋白印迹和APP印迹的重复，已同意撤回。作者无法提供原始数据。编辑和作者j - m。卓和D. Praticò对所提供的数据失去了信心，并认为结论在很大程度上受到了损害。记者无法联系到作者J. Chu，告知他们撤稿的消息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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RETRACTION: Transcriptional Regulation of βsecretase-1 by 12/15-Lipoxygenase Results in Enhanced Amyloidogenesis and Cognitive Impairments.

Retraction: J. Chu , J.-M. Zhuo and D. Praticò , "Transcriptional Regulation of βsecretase-1 by 12/15-Lipoxygenase Results in Enhanced Amyloidogenesis and Cognitive Impairments," Annals of Neurology 71, no. 1 (2012): 57-67, https://doi.org/10.1002/ana.22625. The above article, published online on 12 September 2011 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, J.-M. Zhuo and D. Praticò; the journal Editor-in-Chief, Kenneth L. Tyler; the American Neurological Association and Wiley Periodicals LLC. The retraction has been agreed upon due to the duplication of the actin blots and one of the APP blots shown in figures 2A and 4A. The authors were unable to provide the original data. The editors and the authors, J.-M. Zhuo and D. Praticò, have lost confidence in the data presented and consider the conclusions to be substantially compromised. The author, J. Chu, could not be contacted to inform them of the retraction.

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来源期刊

Annals of Neurology 医学-临床神经学

CiteScore

18.00

自引率

1.80%

发文量

270

审稿时长

3-8 weeks

期刊介绍： Annals of Neurology publishes original articles with potential for high impact in understanding the pathogenesis, clinical and laboratory features, diagnosis, treatment, outcomes and science underlying diseases of the human nervous system. Articles should ideally be of broad interest to the academic neurological community rather than solely to subspecialists in a particular field. Studies involving experimental model system, including those in cell and organ cultures and animals, of direct translational relevance to the understanding of neurological disease are also encouraged.