A sequential Au(I)/TBAF-promoted rapid and selective functionalization of heteroarene N-oxides with alkynes.

We present a rapid and versatile Au(I)-catalyzed strategy for functionalizing N-heteroarenes using TBAF as a nucleophile or base, enabling varied transformations. The method accommodates diverse substrates, offering excellent yields and functional group tolerance. Distinct reaction pathways highlight its adaptability, expanding chemical diversity for organic synthesis.