Decarboxylative Cross-Coupling of Aryl Carboxylic Acids with Arylboronic Acids Using Ag/ZnO Catalyst under Aerobic Conditions in Aqueous Medium

Recently, transition metal-catalyzed decarboxylative cross-coupling reactions have become a novel and crucial category of organic transformations. These reactions have practical applications in constructing carbon–carbon bonds. This study presents the efficient catalytic activity of Ag/ZnO nanoparticles that were synthesized and used as a heterogeneous catalyst in the carbon–carbon bond formation starting from carboxylic acids. By utilizing the heterogeneous Ag catalyst system, the Suzuki–Miyaura coupling reaction was effectively carried out in an aqueous environment, resulting in the formation of coupling products with high yields in a relatively short period of time. The Ag/ZnO nanoparticles were thoroughly characterized using various techniques, and inductively coupled plasma. The findings affirm that the prepared catalyst, comprising Ag/ZnO nanoparticles, exhibits exceptional efficiency and selectivity, with the added advantage of being recyclable multiple times without a significant decline in catalytic activity.