用于聚合诱导自组装（PISA）的超快可控可见光介导光干涉RAFT聚合设计

IF 16.1 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Angewandte Chemie International Edition Pub Date : 2025-01-15 DOI:10.1002/anie.202422975

Zilong Wu, Zhengyan He, Yuchen Zhou, Tongtong Kou, Kaili Gong, Fuchun Nan, Terefe Tafese Bezuneh, Shiguo Han, Cyrille Andre Jean Marie Boyer, William W. Yu

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引用次数: 0

摘要

在这篇论文中，我们设计了一种新的黄药RAFT剂，通过引入（5,6,7,8-四氢-2-萘基）氧（TNO）作为Z基团，即2-[（（5,6,7,8-四氢-2-萘基）氧羰基）硫代)丙酸乙酯]（TNXEP）。由于TNO基团的存在，TNXEP在紫光（λ = 405 nm）和蓝光（λ = 450 nm）下实现了高度可控和超快的光干扰素RAFT聚合。这种方法被有效地扩展到水介质中进行聚合诱导自组装（PISA），促进了聚合物纳米颗粒的合成。利用TNXEP的快速光解和扩展吸收，我们展示了第一个实现超快聚合的光干涉PISA系统(>；90%的单体转化率（分钟）在可见光照射下。增强的可见光穿透性提高了光聚合的均匀性，能够在10分钟内快速、可扩展地生产30克规模的聚合物纳米颗粒，具有可调的形态，包括球体、蠕虫和囊泡。

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Design of an Ultrafast and Controlled Visible Light-Mediated Photoiniferter RAFT Polymerization for Polymerization-Induced Self-Assembly (PISA)

In this contribution, we designed a new xanthate RAFT agent by introducing (5,6,7,8-tetrahydro-2-naphthalenyl)oxy (TNO) as the Z group, namely 2-[(((5,6,7,8-Tetrahydro-2-naphthalenyl)oxycarbonothioyl)thio)ethyl propanoate] (TNXEP). Due to the presence of the TNO group, TNXEP enabled highly controlled and ultrafast photoiniferter RAFT polymerization under violet (λ = 405 nm) and blue (λ = 450 nm) light. This approach was effectively extended to aqueous media for polymerization-induced self-assembly (PISA), facilitating the synthesis of polymeric nanoparticles. Leveraging the rapid photolysis and extended absorption of TNXEP, we demonstrated the first photoiniferter PISA system realizing ultrafast polymerization (> 90% monomer conversion in minutes) under visible light irradiation. Enhanced visible light penetration improved photopolymerization uniformity, enabling rapid and scalable production of polymeric nanoparticles at a 30 g scale in just 10 minutes, with tunable morphologies, including spheres, worms, and vesicles.

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来源期刊

Angewandte Chemie International Edition 化学-化学综合

CiteScore

26.60

自引率

6.60%

发文量

3549

审稿时长

1.5 months

期刊介绍： Angewandte Chemie, a journal of the German Chemical Society (GDCh), maintains a leading position among scholarly journals in general chemistry with an impressive Impact Factor of 16.6 (2022 Journal Citation Reports, Clarivate, 2023). Published weekly in a reader-friendly format, it features new articles almost every day. Established in 1887, Angewandte Chemie is a prominent chemistry journal, offering a dynamic blend of Review-type articles, Highlights, Communications, and Research Articles on a weekly basis, making it unique in the field.