2 -异氰苯丙酯和4 -羟基- 2H - chromen - 2 - ones的正式[3+1+1+1]环化：喹啉融合多环骨架的途径

IF 4.4 2区化学 Q2 CHEMISTRY, APPLIED

Advanced Synthesis & Catalysis Pub Date : 2025-03-04 DOI:10.1002/adsc.202401462

Yu Xing , Xiangheng Li , Zihan Ni , Jiajian Guo , Zijun Zhou , Lei Cui , Chunju Li , Jian Li

引用次数: 0

摘要

一个涉及2 -异氰苯丙酯和4 -羟基- 2H - chromen - 2 - one的级联反应已被记录。该反应生成了高度应变的环丙烯亚胺，从而为合成喹啉融合的多环骨架提供了一条有效途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Formal [3+1+1+1] Annulation of 2‐Isocyanophenyl Propargylic Esters and 4‐Hydroxy‐2H‐Chromen‐2‐Ones: An Access to Quinoline‐Fused Polycyclic Skeletons

A cascade reaction involving 2‐isocyanophenyl propargylic ester and 4‐hydroxy‐2H‐chromen‐2‐one has been documented. This reaction leads to the formation of a highly strained cyclopropen‐imine species, thereby offering an efficient route to synthesize quinoline‐fused polycyclic skeletons.

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来源期刊

Advanced Synthesis & Catalysis 化学-应用化学

CiteScore

9.40

自引率

7.40%

发文量

447

审稿时长

1.8 months

期刊介绍： Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry. The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.