肛肠畸形手术患者术后并发症分析:是否有易感因素?

A Hernández Pérez, P Deltell Collomer, C Abril Sánchez, A Encinas Goenechea, J Gonzálvez Piñera, M Dore Reyes, I Martínez Castaño, P Alcaraz Jiménez, V Díaz Diaz, M G Toro Rodríguez
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摘要

目的:总结我院治疗肛肠畸形(ARM)的经验,分析其并发症及危险因素。材料与方法:对2006 ~ 2023年0 ~ 18岁接受手术治疗的ARM患者进行回顾性研究。收集人口统计学变量、相关畸形、年龄和修复手术手术次数、结肠造口术的存在和类型、既往肠道准备、手术并发症的存在和类型——肠闭塞、肛门脱垂、狭窄、出血、开裂、挤压、肛门成形术错位、尿道穿孔和造口并发症。结果:89例患者纳入研究。男孩44例,女孩45例。中位年龄为7岁(3-18岁)。基线治疗为61例(69%)患者的后矢状肛肠成形术(PSARP)和24例(27%)患者的结肠造口术(4/24环,1/24 Hartmann, 19/24分端)。PSARP的中位年龄为5.4个月(5天-7岁),平均手术时间为112分钟(38-259)。并发症发生率为38%(34/89)。最常见的并发症是肛门脱垂(19%)(1/3因疼痛/出血而再次干预),其次是肛裂(17%)。肠道准备(p= 0.001, -1.49 95% CI: -2.69 ~ -1.24)、存在结肠造口(p= 0.05, -2,54 95% CI: -6.5 ~ -0.987)和手术修复年龄(p= 0.047, 1.198 95% CI: 1.1 ~ 3.15)与并发症发生率之间的差异具有统计学意义。年龄-并发症相关评分为0.21 (p= 0.046)。两组手术时间(p= 0.073)和造口方式(p= 0.81)差异无统计学意义。结论:38%的患者出现并发症。肠道准备、结肠造口术的存在和修复的年龄对并发症的发生率有影响。前两者可作为保护因素(RR分别为-1,49和-2.54)。年龄会使风险增加1.2倍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of postoperative complications in patients undergoing anorectal malformation surgery: are there any predisposing factors?

Objective: To describe our experience with anorectal malformation (ARM) patients, while analyzing complications and risk factors.

Materials and methods: A retrospective study of ARM patients aged 0-18 years old undergoing surgery from 2006 to 2023 was carried out. Demographic variables, associated malformations, age and repair surgery operating times, presence and type of colostomy, previous intestinal preparation, and presence and type of surgical complications -intestinal occlusion, anal prolapse, stenosis, bleeding, dehiscence, extrusion, anoplasty misposition, urethral perforation, and stomal complications- were collected.

Results: 89 patients were studied. 44 patients were boys and 45 were girls. Median age was 7 years (3-18). Baseline treatment was posterior sagittal anorectoplasty (PSARP) in 61 (69%) patients, and colostomy in 24 (27%) patients (4/24 loop, 1/24 Hartmann, 19/24 divided ends). Median age at PSARP was 5.4 months (5 days-7 years), with a mean operating time of 112 min (38-259). The incidence of complications was 38% (34/89). The most frequent complication was anal prolapse (19%) (1/3 reintervention as a result of pain/bleeding), followed by dehiscence (17%). Statistically significant differences were noted between intestinal preparation (p= 0.001, -1.49 95% CI: -2.69 to -1.24), presence of colostomy (p= 0.05, -2,54 95% CI: -6.5 to -0.987), and age at surgical repair (p= 0.047, 1.198 95% CI: 1.1 to 3.15) with the incidence of complications. The age-complications correlation score was 0.21 (p= 0.046). No differences in terms of operating time (p= 0.073) and type of colostomy (p= 0.81) were observed.

Conclusions: 38% of the patients had complications. Intestinal preparation, presence of colostomy, and age at repair can have an impact on the incidence of complications. The first two could stand as protective factors (RR= -1,49 and -2.54, respectively). Age would increase the risk by 1.2-fold.

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