Optical Metasurfaces for Biomedical Imaging and Sensing

Optical metasurfaces, arrays of nanostructures engineered to manipulate light, have emerged as a transformative technology in both research and industry due to their compact design and exceptional light control capabilities. Their strong light–matter interactions enable precise wavefront modulation, polarization control, and significant near-field enhancements. These unique properties have recently driven their application in biomedical fields. In particular, metasurfaces have led to breakthroughs in biomedical imaging technologies, such as achromatic imaging, phase imaging, and extended depth-of-focus imaging. They have also advanced cutting-edge biosensing technologies, featuring high-quality factor resonators and near-field enhancements. As the demand for device miniaturization and system integration increases, metasurfaces are expected to play a pivotal role in the development of next-generation biomedical devices. In this review, we explore the latest advancements in the use of metasurfaces for biomedical applications, with a particular focus on imaging and sensing. Additionally, we discuss future directions aimed at transforming the biomedical field by leveraging the full potential of metasurfaces to provide compact, high-performance solutions for a wide range of applications.